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Literature DB >> 24727245

Signaling regulations of neuronal regenerative ability.

Abstract

Different from physiological axon growth during development, a major limiting factor for successful axon regeneration is the poor intrinsic regenerative capacity in mature neurons in the adult mammalian central nervous system (CNS). Recent studies identified several molecular pathways, including PTEN/mTOR, Jak/STAT, DLK/JNK, providing important probes in investigating the mechanisms by which the regenerative ability is regulated. This review will summarize these recent findings and speculate their implications.

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Year: 2014 PMID： 24727245 PMCID： PMC4546824 DOI： 10.1016/j.conb.2014.03.007

Source DB: PubMed Journal: Curr Opin Neurobiol ISSN： 0959-4388 Impact factor: 6.627

100 in total

1. Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration.

Authors: Jung Eun Shin; Yongcheol Cho; Bogdan Beirowski; Jeffrey Milbrandt; Valeria Cavalli; Aaron DiAntonio
Journal: Neuron Date: 2012-06-21 Impact factor: 17.173

Review 2. The challenges of long-distance axon regeneration in the injured CNS.

Authors: Daniel J Chew; James W Fawcett; Melissa R Andrews
Journal: Prog Brain Res Date: 2012 Impact factor: 2.453

3. Long-distance growth and connectivity of neural stem cells after severe spinal cord injury.

Authors: Paul Lu; Yaozhi Wang; Lori Graham; Karla McHale; Mingyong Gao; Di Wu; John Brock; Armin Blesch; Ephron S Rosenzweig; Leif A Havton; Binhai Zheng; James M Conner; Martin Marsala; Mark H Tuszynski
Journal: Cell Date: 2012-09-14 Impact factor: 41.582

Review 4. Defeating inhibition of regeneration by scar and myelin components.

Authors: James W Fawcett; Martin E Schwab; Laura Montani; Nicole Brazda; Hans Werner Müller
Journal: Handb Clin Neurol Date: 2012

5. No simpler than mammals: axon and dendrite regeneration in Drosophila.

Authors: Homaira Nawabi; Katherine Zukor; Zhigang He
Journal: Genes Dev Date: 2012-07-15 Impact factor: 11.361

6. HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration.

Authors: Yongcheol Cho; Valeria Cavalli
Journal: EMBO J Date: 2012-06-12 Impact factor: 11.598

7. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam.

Authors: Yuanquan Song; Kassandra M Ori-McKenney; Yi Zheng; Chun Han; Lily Yeh Jan; Yuh Nung Jan
Journal: Genes Dev Date: 2012-07-03 Impact factor: 11.361

8. Disruption of E3 ligase NEDD4 in peripheral neurons interrupts axon outgrowth: Linkage to PTEN.

Authors: Kimberly J Christie; Jose A Martinez; Douglas W Zochodne
Journal: Mol Cell Neurosci Date: 2012-04-26 Impact factor: 4.314

9. Regulation of DLK-1 kinase activity by calcium-mediated dissociation from an inhibitory isoform.

Authors: Dong Yan; Yishi Jin
Journal: Neuron Date: 2012-11-08 Impact factor: 17.173

10. microRNA-222 targeting PTEN promotes neurite outgrowth from adult dorsal root ganglion neurons following sciatic nerve transection.

Authors: Songlin Zhou; Dingding Shen; Yongjun Wang; Leilei Gong; Xiaoyan Tang; Bin Yu; Xiaosong Gu; Fei Ding
Journal: PLoS One Date: 2012-09-13 Impact factor: 3.240

55 in total

Review 1. The back and forth of axonal injury and repair after stroke.

Authors: Jason D Hinman
Journal: Curr Opin Neurol Date: 2014-12 Impact factor: 5.710

2. Upregulating Lin28a Promotes Axon Regeneration in Adult Mice with Optic Nerve and Spinal Cord Injury.

Authors: Fatima M Nathan; Yosuke Ohtake; Shuo Wang; Xinpei Jiang; Armin Sami; Hua Guo; Feng-Quan Zhou; Shuxin Li
Journal: Mol Ther Date: 2020-04-15 Impact factor: 11.454

3. Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity.

Authors: Marco Leibinger; Anastasia Andreadaki; Renate Golla; Evgeny Levin; Alexander M Hilla; Heike Diekmann; Dietmar Fischer
Journal: Proc Natl Acad Sci U S A Date: 2017-06-19 Impact factor: 11.205

4. Promoting Axon Regeneration in Adult CNS by Targeting Liver Kinase B1.

Authors: Yosuke Ohtake; Armin Sami; Xinpei Jiang; Makoto Horiuchi; Kieran Slattery; Lena Ma; George M Smith; Michael E Selzer; Shin-Ichi Muramatsu; Shuxin Li
Journal: Mol Ther Date: 2018-11-01 Impact factor: 11.454

5. Effects of PTEN and Nogo Codeletion on Corticospinal Axon Sprouting and Regeneration in Mice.

Authors: Cédric G Geoffroy; Ariana O Lorenzana; Jeffrey P Kwan; Kyle Lin; Omeed Ghassemi; Andrew Ma; Nuo Xu; Daniel Creger; Kai Liu; Zhigang He; Binhai Zheng
Journal: J Neurosci Date: 2015-04-22 Impact factor: 6.167

6. Evidence for an Age-Dependent Decline in Axon Regeneration in the Adult Mammalian Central Nervous System.

Authors: Cédric G Geoffroy; Brett J Hilton; Wolfram Tetzlaff; Binhai Zheng
Journal: Cell Rep Date: 2016-03-31 Impact factor: 9.423

Review 7. Transcriptional regulation of APP by apoE: To boldly go where no isoform has gone before: ApoE, APP transcription and AD: Hypothesised mechanisms and existing knowledge gaps.

Authors: Liying Corinne Lee; Michele Q L Goh; Edward H Koo
Journal: Bioessays Date: 2017-07-21 Impact factor: 4.345

Review 8. The age factor in axonal repair after spinal cord injury: A focus on neuron-intrinsic mechanisms.

Authors: Cédric G Geoffroy; Jessica M Meves; Binhai Zheng
Journal: Neurosci Lett Date: 2016-11-03 Impact factor: 3.046

9. Tubulin-tyrosine Ligase (TTL)-mediated Increase in Tyrosinated α-Tubulin in Injured Axons Is Required for Retrograde Injury Signaling and Axon Regeneration.

Authors: Wenjun Song; Yongcheol Cho; Dana Watt; Valeria Cavalli
Journal: J Biol Chem Date: 2015-04-24 Impact factor: 5.157

10. Applying proteomics to research for optic nerve regeneration in glaucoma: what's on the horizon?

Authors: Gülgün Tezel
Journal: Expert Rev Proteomics Date: 2016-09-24 Impact factor: 3.940