Literature DB >> 24726783

Survey of pediatric urologists on the preoperative use of testosterone in the surgical correction of hypospadias.

Rena D Malik1, Dennis B Liu2.   

Abstract

OBJECTIVE: To better characterize the current state of testosterone use in the surgical correction of hypospadias among pediatric urologists.
METHODS: An email was sent via the pedsurology research listserv through the American Academy of Pediatrics, inviting members to participate in an anonymous survey regarding their use of preoperative testosterone in hypospadias correction.
RESULTS: Twenty-seven responses were obtained for a response rate of 53%. Almost all responders practiced in North America, had exclusively pediatric patients in their practice, and had been in practice for 30 years or less. 55% were classified as high-volume surgeons, completing >50 cases yearly, 87% of whom use preoperative androgen therapy currently, compared with 67% of low-volume surgeons. Testosterone was prescribed primarily for a small appearing penis, reduced glans circumference, reduced urethral plate width, and/or proximal hypospadias. The effect of testosterone was determined primarily by evaluating penile appearance (59%). However, the majority (56%) of physicians stopped giving testosterone when they completed a predetermined regimen.
CONCLUSIONS: While many pediatric urologists use testosterone prior to hypospadias repair, the practice patterns are variable. It appears that the use of testosterone is primarily limited to patients with proximal hypospadias, small appearing penis, reduced glans circumference or reduced urethral plate.
Copyright © 2014 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Hypospadias; Practice patterns; Testosterone

Mesh:

Substances:

Year:  2014        PMID: 24726783     DOI: 10.1016/j.jpurol.2014.02.008

Source DB:  PubMed          Journal:  J Pediatr Urol        ISSN: 1477-5131            Impact factor:   1.830


  9 in total

Review 1.  Current hypospadias management: Diagnosis, surgical management, and long-term patient-centred outcomes.

Authors:  Melise A Keays; Sumit Dave
Journal:  Can Urol Assoc J       Date:  2017 Jan-Feb       Impact factor: 1.862

Review 2.  [Disorders of sex development and proximal hypospadias].

Authors:  J Oswald
Journal:  Urologe A       Date:  2016-01       Impact factor: 0.639

3.  Effects of oral testosterone undecanoate treatment for severe hypospadias.

Authors:  Chao Chen; Chun-Xiu Gong; Wei-Ping Zhang
Journal:  Int Urol Nephrol       Date:  2015-04-17       Impact factor: 2.370

4.  Management of Proximal Hypospadias with 2-Stage Repair: 20-Year Experience.

Authors:  Erin R McNamara; Anthony J Schaeffer; Tanya Logvinenko; Catherine Seager; Ilina Rosoklija; Caleb P Nelson; Alan B Retik; David A Diamond; Marc Cendron
Journal:  J Urol       Date:  2015-05-09       Impact factor: 7.450

Review 5.  The influence of pre-operative hormonal stimulation on hypospadias repair.

Authors:  Nathan C Wong; Luis H Braga
Journal:  Front Pediatr       Date:  2015-04-22       Impact factor: 3.418

6.  Can Testosterone Alter the Degree of Hypospadias? A Comprehensive Study.

Authors:  Dasmit Singh Khokar; Ravi Vadilal Patel
Journal:  J Indian Assoc Pediatr Surg       Date:  2021-01-11

7.  Results of two-stage transverse preputial island flap urethroplasty for proximal hypospadias with chordee that mandate division of the urethral plate.

Authors:  Mostafa M Ali; Mamdouh M El-Hawy; Ehab M Galal; Ehab R Tawfiek; Ahmed Z Anwar
Journal:  Cent European J Urol       Date:  2021-01-15

Review 8.  Defining the role of pre-operative hormonal therapy in hypospadias.

Authors:  Kiarash Taghavi; Lomani A O'Hagan; Jacqueline K Hewitt; Pierre DE Mouriquand
Journal:  J Paediatr Child Health       Date:  2022-07-06       Impact factor: 1.929

Review 9.  The role of pre-operative androgen stimulation in hypospadias surgery.

Authors:  Cevdet Kaya; Christian Radmayr
Journal:  Transl Androl Urol       Date:  2014-12
  9 in total

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