| Literature DB >> 2472582 |
J I Sage1, D M McHale, P Sonsalla, D Vitagliano, R E Heikkila.
Abstract
We report the clinical spectrum of 3 patients with Parkinson's disease who experienced complex patterns of levodopa-related dystonia. Dystonia was unrelieved by multiple medication regimens but responded well to continuous, duodenal levodopa infusions. Patients were able to remain mobile without severe dystonia despite a very narrow window of benefit between the levodopa concentration necessary to achieve the "on" state and that which caused the onset of dystonic spasms.Entities:
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Year: 1989 PMID： 2472582 DOI： 10.1212/wnl.39.7.888
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910