Literature DB >> 24725490

The epidemiology and clinical implications of genetic variation in prostate cancer.

Brian T Helfand1, William J Catalona2.   

Abstract

There is strong evidence of a genetic predisposition to prostate cancer. Recent advances in genetic sequencing technologies have permitted significant advances in the field. This article reviews the genetic basis underlying prostate cancer, and highlights the epidemiology and potential clinical usefulness of both rare and common genetic variations. In addition, recent findings related to the understanding of prostate cancer genetics are discussed.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Genetic variants; Prostate cancer; Susceptibility; Tumor aggressiveness

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Year:  2014        PMID： 24725490     DOI： 10.1016/j.ucl.2014.01.001

Source DB:  PubMed          Journal:  Urol Clin North Am        ISSN： 0094-0143            Impact factor:   2.241


  5 in total

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Journal:  Life Sci       Date:  2016-03-24       Impact factor: 5.037

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Review 4.  Association between insulin-like growth factor-binding protein-3 polymorphism-202 A/C and the risk of prostate cancer: a meta-analysis.

Authors:  Zhiqiang Qin; Xiao Li; Jingyuan Tang; Xuping Jiang; Yajie Yu; Chengming Wang; Weizhang Xu; Yibo Hua; Bin Yu; Wei Zhang
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Review 5.  Clinical validity and utility of genetic risk scores in prostate cancer.

Authors:  Brian T Helfand; James Kearns; Carly Conran; Jianfeng Xu
Journal:  Asian J Androl       Date:  2016 Jul-Aug       Impact factor: 3.285
  5 in total

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