Literature DB >> 2472543

Cloning of Plasmodium yoelii genes expressing three different sporozoite-specific antigens.

A Wortman1, P Rogers, Y Charoenvit, A McDermott, M Leef, M Sedegah, R L Beaudoin.   

Abstract

Genomic DNA isolated from Plasmodium yoelii (strain #17XNL) was prepared by partial digestion and cloned in Escherichia coli TB-1 with pUC18 plasmid. Antigen-producing recombinants were detected by a battery of monoclonal antibodies against antigens of the sporozoite stages. Four clones producing stage-specific sporozoite antigens were identified. One produced P. yoelii circumsporozoite protein, and three produced other P. yoelii sporozoite antigens.

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Year:  1989        PMID： 2472543     DOI： 10.1016/0882-4010(89)90072-7

Source DB:  PubMed          Journal:  Microb Pathog        ISSN： 0882-4010            Impact factor:   3.738


  5 in total

1.  A malaria sporozoite surface antigen distinct from the circumsporozoite protein.

Authors:  R C Hedstrom; J R Campbell; M L Leef; Y Charoenvit; M Carter; M Sedegah; R L Beaudoin; S L Hoffman
Journal:  Bull World Health Organ       Date:  1990       Impact factor: 9.408

2.  Evaluation of vaccines designed to induce protective cellular immunity against the Plasmodium yoelii circumsporozoite protein: vaccinia, pseudorabies, and Salmonella transformed with circumsporozoite gene.

Authors:  M Sedegah; R L Beaudoin; W R Majarian; M D Cochran; C H Chiang; J Sadoff; A Aggarwal; Y Charoenvit; S L Hoffman
Journal:  Bull World Health Organ       Date:  1990       Impact factor: 9.408

3.  Evidence for diversity of Plasmodium falciparum sporozoite surface antigens derived from analysis of antibodies elicited in humans.

Authors:  B Galey; P Druilhe; I Ploton; C Desgranges; A Asavanich; T Harinasuta; C Marchand; K Brahimi; Y Charoenvit; C Paul
Journal:  Infect Immun       Date:  1990-09       Impact factor: 3.441

4.  Active and passive immunization against Plasmodium yoelii sporozoites.

Authors:  Y Charoenvit; M Sedegah; L F Yuan; M Gross; C Cole; R Bechara; M F Leef; F A Robey; G H Lowell; R L Beaudoin
Journal:  Bull World Health Organ       Date:  1990       Impact factor: 9.408

5.  Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

Authors:  M Sedegah; R Hedstrom; P Hobart; S L Hoffman
Journal:  Proc Natl Acad Sci U S A       Date:  1994-10-11       Impact factor: 11.205
  5 in total

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