Literature DB >> 24725377

Bile cast nephropathy: an often forgotten diagnosis.

Adrian Sequeira1, Xin Gu.   

Abstract

High bilirubin levels are nephrotoxic. Bilirubin can cause a functional proximal tubulopathy or may precipitate into casts associated with acute tubular injury. This condition is known as bile cast nephropathy. The kidney injury is generally reversible if bilirubin levels are decreased early. We present a case wherein an alcoholic patient presented with high bilirubin levels and anuric acute kidney injury. The initial urine analysis suggested intrinsic renal disease. A kidney biopsy, performed a few days after the initiation of dialysis, demonstrated the presence of bile casts along with acute tubular injury. The patient however continued to be dialysis dependent inspite of initiating prednisolone to treat acute alcoholic hepatitis.
© 2014 International Society for Hemodialysis.

Entities:  

Keywords:  Bilirubin; bile; cast; tubulopathy

Mesh:

Year:  2014        PMID: 24725377     DOI: 10.1111/hdi.12169

Source DB:  PubMed          Journal:  Hemodial Int        ISSN: 1492-7535            Impact factor:   1.812


  9 in total

Review 1.  Reappraising the spectrum of AKI and hepatorenal syndrome in patients with cirrhosis.

Authors:  Juan Carlos Q Velez; George Therapondos; Luis A Juncos
Journal:  Nat Rev Nephrol       Date:  2019-11-13       Impact factor: 28.314

2.  Murine epithelial sodium (Na+) channel regulation by biliary factors.

Authors:  Xue-Ping Wang; Seohyun Janice Im; Deidra M Balchak; Nicolas Montalbetti; Marcelo D Carattino; Evan C Ray; Ossama B Kashlan
Journal:  J Biol Chem       Date:  2019-05-15       Impact factor: 5.157

Review 3.  Bile Cast Nephropathy: A Comprehensive Review.

Authors:  Manoj R Somagutta; Molly S Jain; Maria Kezia Lourdes Pormento; Siva K Pendyala; Narayana Reddy Bathula; Nagendrababu Jarapala; Ashwini Mahadevaiah; Nayana Sasidharan; Mohamed A Gad; Greta Mahmutaj; Namrata Hange
Journal:  Cureus       Date:  2022-03-29

Review 4.  Bile cast nephropathy: A case report and review of the literature.

Authors:  Jaymon Patel; Saqib Walayat; Nikhil Kalva; Sidney Palmer-Hill; Sonu Dhillon
Journal:  World J Gastroenterol       Date:  2016-07-21       Impact factor: 5.742

5.  Urinary bile casts in bile cast nephropathy secondary to severe falciparum malaria.

Authors:  Manoj Kumar Mohapatra; Ashok Kumar Behera; Purna Chandra Karua; Prafulla Kumar Bariha; Ashutosh Rath; Kailash Chandra Aggrawal; Snigdha Rani Nahak; Santosh Shankar Gudaganatti
Journal:  Clin Kidney J       Date:  2016-06-05

6.  Bile Cast Nephropathy in Patients with Acute Kidney Injury Due to Hepatorenal Syndrome: A Postmortem Kidney Biopsy Study.

Authors:  Suman Lata Nayak; Manoj Kumar; Chhagan Bihari; Archana Rastogi
Journal:  J Clin Transl Hepatol       Date:  2017-05-04

7.  [Nephrotoxicity secondary to hyperbilirubinemia: report of a case].

Authors:  Med Taieb Jomni; Mouna Largueche; Badreddine Ben Kaab; Imen Abdelaal; Syrine Bellakhal; Med Hédi Douggui
Journal:  Pan Afr Med J       Date:  2015-11-27

8.  Bile Nephropathy in Flucloxacillin-Induced Cholestatic Liver Dysfunction.

Authors:  Basil Alnasrallah; John F Collins; L Jonathan Zwi
Journal:  Case Rep Nephrol       Date:  2016-02-24

9.  Bile cast nephropathy in a patient with cholangiocarcinoma - a case report.

Authors:  Kittrawee Kritmetapak; Thanatarn Sathidatekoonchorn; Weerapat Papanrueng
Journal:  Clin Case Rep       Date:  2018-03-05
  9 in total

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