Literature DB >> 24725151

Pd-catalyzed oxidative annulation of hydrazides with isocyanides: synthesis of 2-amino-1,3,4-oxadiazoles.

Tao Fang1, Qitao Tan, Zhengwei Ding, Bingxin Liu, Bin Xu.   

Abstract

An efficient palladium-catalyzed oxidative annulation reaction was developed through sequential isocyanide insertions into N-H and O-H bonds of hydrazides, which provides an efficient access to valuable 2-amino-1,3,4-oxadiazoles and their derivatives.

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Year:  2014        PMID: 24725151     DOI: 10.1021/ol5006449

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  6 in total

1.  1,3,4-Oxadiazole and Heteroaromatic-Fused 1,2,4-Triazole Synthesis using Diverted Umpolung Amide Synthesis.

Authors:  Kazuyuki Tokumaru; Kalisankar Bera; Jeffrey N Johnston
Journal:  Synthesis (Stuttg)       Date:  2017-08-07       Impact factor: 3.157

2.  A convergent synthesis of 1,3,4-oxadiazoles from acyl hydrazides under semiaqueous conditions.

Authors:  Kazuyuki Tokumaru; Jeffrey N Johnston
Journal:  Chem Sci       Date:  2017-02-23       Impact factor: 9.825

3.  From Isocyanides to Iminonitriles via Silver-mediated Sequential Insertion of C(sp3)-H Bond.

Authors:  Huiwen Chi; Hao Li; Bingxin Liu; Rongxuan Ye; Haoyang Wang; Yin-Long Guo; Qitao Tan; Bin Xu
Journal:  iScience       Date:  2019-11-01

4.  Novel oxadiazole derivatives as potent inhibitors of α-amylase and α-glucosidase enzymes: Synthesis, in vitro evaluation, and molecular docking studies.

Authors:  Asma Bukhari; Humaira Nadeem; Muhammad Imran; Syed Aun Muhammad
Journal:  Iran J Basic Med Sci       Date:  2021-12       Impact factor: 2.699

5.  Synthesis of 2-Imino-1,3,4-oxadiazolines from Acylhydrazides and Isothiocyanates via Aerobic Oxidation and a DMAP-Mediated Annulation Sequence.

Authors:  Jae Hyeok Lim; Sang Eun Baek; Bapurao Sudam Lad; Jinho Kim
Journal:  ACS Omega       Date:  2022-08-01

Review 6.  Recent Advances in Palladium-Catalyzed Isocyanide Insertions.

Authors:  Jurriën W Collet; Thomas R Roose; Bram Weijers; Bert U W Maes; Eelco Ruijter; Romano V A Orru
Journal:  Molecules       Date:  2020-10-23       Impact factor: 4.411

  6 in total

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