| Literature DB >> 24724944 |
Andrej V Matsnev1, Si-Yan Qing, Mark A Stanton, Kyle A Berger, Günter Haufe, Joseph S Thrasher.
Abstract
Three novel, easily scalable routes for the synthesis of pentafluorosulfanyldifluoroacetic acid, SF5CF2C(O)OH, are described. Reactions of its acid chloride with amines and alcohols led to a small library of 15 amides and five esters, respectively. The reaction of the acid chloride with phenylmagnesium bromide gave the corresponding acetophenone. Pentafluorosulfanyldifluoroacetonitrile was obtained from pentafluorosulfanyldifluoroacetamide by dehydration with diphosphorus pentoxide.Entities:
Year: 2014 PMID： 24724944 DOI： 10.1021/ol500766v
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005