Peter Y Chang1,2, Zvi Kresch1,2, C Michael Samson1,2, Ronald C Gentile1,2,3. 1. a Department of Ophthalmology , The New York Eye & Ear Infirmary of Mt. Sinai , New York , USA . 2. b Icahn School of Medicine at Mount Sinai , New York , NY , USA , and. 3. c Department of Ophthalmology , Winthrop University Hospital , Mineola , New York , USA.
Abstract
PURPOSE: To report two cases of spontaneous Retisert implant dissociation with dislocation of the medication reservoir into the anterior chamber. DESIGN AND METHODS: Case reports. RESULTS: Two patients with chronic, noninfectious uveitis following Retisert implantation between 6 and 7 years prior presented with a complaint of a "white spot" in their right eyes. Both patients had previous pars plana vitrectomies. Anterior segment examination revealed a dislocated medication reservoir of the Retisert implant in the inferior portion of anterior chamber with associated reservoir-corneal endothelial touch and stromal edema. The reservoirs were subsequently retrieved via a pars plana approach and removed from the anterior chamber through a corneal incision. CONCLUSIONS: Spontaneous dissociation of the Retisert implant with dislocation of the medication reservoir into the anterior chamber can be a late complication of Retisert implantation. Eye care professionals and patients should be aware of this complication, particularly with long-term intraocular retention of this device.
PURPOSE: To report two cases of spontaneous Retisert implant dissociation with dislocation of the medication reservoir into the anterior chamber. DESIGN AND METHODS: Case reports. RESULTS: Two patients with chronic, noninfectious uveitis following Retisert implantation between 6 and 7 years prior presented with a complaint of a "white spot" in their right eyes. Both patients had previous pars plana vitrectomies. Anterior segment examination revealed a dislocated medication reservoir of the Retisert implant in the inferior portion of anterior chamber with associated reservoir-corneal endothelial touch and stromal edema. The reservoirs were subsequently retrieved via a pars plana approach and removed from the anterior chamber through a corneal incision. CONCLUSIONS: Spontaneous dissociation of the Retisert implant with dislocation of the medication reservoir into the anterior chamber can be a late complication of Retisert implantation. Eye care professionals and patients should be aware of this complication, particularly with long-term intraocular retention of this device.
Authors: Lea F Weber; Stefanie Marx; Gerd U Auffarth; Alexander F Scheuerle; Tamer Tandogan; Christian Mayer; Ramin Khoramnia Journal: J Ophthalmic Inflamm Infect Date: 2019-01-29