Literature DB >> 24724563

High-resolution melting assay for genotyping of IFNL4-associated dinucleotide variant rs368234815.

E Galmozzi1, F Facchetti, R Perbellini, A Aghemo.   

Abstract

Interferon-λ4-related dinucleotide variant rs368234815 TT/-G is strongly linked with rs12979860 polymorphism, the most important genetic marker connected to treatment-induced hepatitis C virus clearance. Due to additional baseline information that rs368234815 polymorphism could provide for the management of chronic hepatitis C, we developed and validated a high-resolution melting genotyping assay using 193 patients with chronic hepatitis C.
© 2014 The Authors Clinical Microbiology and Infection © 2014 European Society of Clinical Microbiology and Infectious Diseases.

Entities:  

Keywords:  IFNL4; IL28B; RT-PCR; hepatitis C virus; high-resolution melting

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Substances：

Year:  2014        PMID： 24724563     DOI： 10.1111/1469-0691.12637

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN： 1198-743X            Impact factor:   8.067


  1 in total

1.  Interferon λ 3 and 4 Genotyping Using High-Resolution Melt Curve Analysis Suitable for Multiple Clinical Sample Types.

Authors:  François M J Lamoury; Sofia Bartlett; Brendan Jacka; Behzad Hajarizadeh; Jason Grebely; Gail V Matthews; Gregory J Dore; Tanya L Applegate
Journal:  J Mol Diagn       Date:  2015-07-04       Impact factor: 5.568
  1 in total

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