Aaron W James1, Le Chang1, Benjamin Levine2, Sarah M Dry1. 1. Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. 2. Department of Radiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Abstract
INTRODUCTION: Alveolar soft part sarcoma (ASPS) commonly arises in the soft tissue of the lower extremities. Primary bone involvement is rare. METHODS/ RESULTS: We report a 23-year-old male who presented with pathologic fracture of the clavicle, and diagnosis of clavicular ASPS. Workup demonstrated a lumbar meningeal mass, also involving the vertebral bodies. CONCLUSIONS: Few cases of primary bone ASPS have been identified. Most common primary bone involvement includes the fibula, ilium and tibia. Likewise, meningeal involvement is quite rare. In summary, primary bone ASPS is rare and may involve the clavicle. Meningeal involvement is likewise rare, and presumably represents metastatic spread.
INTRODUCTION:Alveolar soft part sarcoma (ASPS) commonly arises in the soft tissue of the lower extremities. Primary bone involvement is rare. METHODS/ RESULTS: We report a 23-year-old male who presented with pathologic fracture of the clavicle, and diagnosis of clavicular ASPS. Workup demonstrated a lumbar meningeal mass, also involving the vertebral bodies. CONCLUSIONS: Few cases of primary bone ASPS have been identified. Most common primary bone involvement includes the fibula, ilium and tibia. Likewise, meningeal involvement is quite rare. In summary, primary bone ASPS is rare and may involve the clavicle. Meningeal involvement is likewise rare, and presumably represents metastatic spread.
Entities:
Keywords:
ASPS; Alveolar soft part sarcoma; Bone ASPS; Meningeal ASPS
Authors: Marc Ladanyi; Cristina R Antonescu; Marija Drobnjak; Ann Baren; Man Yee Lui; David W Golde; Carlos Cordon-Cardo Journal: Am J Pathol Date: 2002-04 Impact factor: 4.307
Authors: Yeong Dae Kim; Chang Hun Lee; Min Ki Lee; Yeon Joo Jeong; Jee Yeon Kim; Do Youn Park; Mee Young Sol Journal: J Korean Med Sci Date: 2007-04 Impact factor: 2.153