Literature DB >> 24719421

Incorporation of mouse APOBEC3 into murine leukemia virus virions decreases the activity and fidelity of reverse transcriptase.

Stefano Boi1, Angelo Kolokithas2, Joyce Shepard2, Rebecca Linwood2, Kyle Rosenke2, Erik Van Dis2, Frank Malik2, Leonard H Evans3.   

Abstract

APOBEC3 proteins are restriction factors that induce G→A hypermutation in retroviruses during replication as a result of cytidine deamination of minus-strand DNA transcripts. However, the mechanism of APOBEC inhibition of murine leukemia viruses (MuLVs) does not appear to be G→A hypermutation and is unclear. In this report, the incorporation of mA3 in virions resulted in a loss in virion reverse transcriptase (RT) activity and RT fidelity that correlated with the loss of virion-specific infectivity.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 24719421      PMCID： PMC4054435          DOI： 10.1128/JVI.00967-14

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

1.  Direct determination of the point mutation rate of a murine retrovirus.

Authors:  R J Monk; F G Malik; D Stokesberry; L H Evans
Journal:  J Virol       Date:  1992-06       Impact factor: 5.103

2.  Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome.

Authors:  Qin Yu; Renate König; Satish Pillai; Kristopher Chiles; Mary Kearney; Sarah Palmer; Douglas Richman; John M Coffin; Nathaniel R Landau
Journal:  Nat Struct Mol Biol       Date:  2004-04-18       Impact factor: 15.369

3.  APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA.

Authors:  Linda Chelico; Phuong Pham; Peter Calabrese; Myron F Goodman
Journal:  Nat Struct Mol Biol       Date:  2006-04-23       Impact factor: 15.369

4.  Murine retrovirus escapes from murine APOBEC3 via two distinct novel mechanisms.

Authors:  Aierken Abudu; Akifumi Takaori-Kondo; Taisuke Izumi; Kotaro Shirakawa; Masayuki Kobayashi; Amane Sasada; Keiko Fukunaga; Takashi Uchiyama
Journal:  Curr Biol       Date:  2006-08-08       Impact factor: 10.834

5.  Differential sensitivity of murine leukemia virus to APOBEC3-mediated inhibition is governed by virion exclusion.

Authors:  Brian P Doehle; Alexandra Schäfer; Heather L Wiegand; Hal P Bogerd; Bryan R Cullen
Journal:  J Virol       Date:  2005-07       Impact factor: 5.103

6.  Feline lentivirus evolution in cross-species infection reveals extensive G-to-A mutation and selection on key residues in the viral polymerase.

Authors:  Mary Poss; Howard A Ross; Sally L Painter; David C Holley; Julie A Terwee; Sue Vandewoude; Allen Rodrigo
Journal:  J Virol       Date:  2006-03       Impact factor: 5.103

7.  Use of a focal immunofluorescence assay on live cells for quantitation of retroviruses: distinction of host range classes in virus mixtures and biological cloning of dual-tropic murine leukemia viruses.

Authors:  M Sitbon; J Nishio; K Wehrly; D Lodmell; B Chesebro
Journal:  Virology       Date:  1985-02       Impact factor: 3.616

8.  Cytidine deamination of retroviral DNA by diverse APOBEC proteins.

Authors:  Kate N Bishop; Rebecca K Holmes; Ann M Sheehy; Nicholas O Davidson; Soo-Jin Cho; Michael H Malim
Journal:  Curr Biol       Date:  2004-08-10       Impact factor: 10.834

9.  Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.

Authors:  Diana S Smith; Kejun Guo; Bradley S Barrett; Karl J Heilman; Leonard H Evans; Kim J Hasenkrug; Warner C Greene; Mario L Santiago
Journal:  PLoS Pathog       Date:  2011-10-06       Impact factor: 6.823

10.  Studies on the restriction of murine leukemia viruses by mouse APOBEC3.

Authors:  Silvia Sanchez-Martinez; Amanda L Aloia; Demetria Harvin; Jane Mirro; Robert J Gorelick; Patric Jern; John M Coffin; Alan Rein
Journal:  PLoS One       Date:  2012-05-29       Impact factor: 3.240
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  10 in total

Review 1.  APOBECs and virus restriction.

Authors:  Reuben S Harris; Jaquelin P Dudley
Journal:  Virology       Date:  2015-03-26       Impact factor: 3.616

2.  Murine Leukemia Virus P50 Protein Counteracts APOBEC3 by Blocking Its Packaging.

Authors:  Wenming Zhao; Charbel Akkawi; Marylène Mougel; Susan R Ross
Journal:  J Virol       Date:  2020-08-31       Impact factor: 5.103

3.  APOBEC3 enzymes restrict marginal zone B cells.

Authors:  Gabriele B Beck-Engeser; Rebecca Winkelmann; Matthew L Wheeler; Maryam Shansab; Philipp Yu; Sarah Wünsche; Anja Walchhütter; Mirjam Metzner; Christian Vettermann; Dan Eilat; Anthony DeFranco; Hans-Martin Jäck; Matthias Wabl
Journal:  Eur J Immunol       Date:  2015-01-21       Impact factor: 5.532

4.  Mouse APOBEC3 expression in NIH 3T3 cells mediates hypermutation of AKV murine leukemia virus.

Authors:  Stefano Boi; Morgan E Ferrell; Ming Zhao; Kim J Hasenkrug; Leonard H Evans
Journal:  Virology       Date:  2018-03-30       Impact factor: 3.616

Review 5.  Mouse knockout models for HIV-1 restriction factors.

Authors:  Jan Rehwinkel
Journal:  Cell Mol Life Sci       Date:  2014-05-23       Impact factor: 9.261

6.  A Protein Antagonist of Activation-Induced Cytidine Deaminase Encoded by a Complex Mouse Retrovirus.

Authors:  Gurvani B Singh; Hyewon Byun; Almas F Ali; Frank Medina; Dennis Wylie; Haridha Shivram; Andrea K Nash; Mary M Lozano; Jaquelin P Dudley
Journal:  mBio       Date:  2019-08-13       Impact factor: 7.867

Review 7.  Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity.

Authors:  Ulf Dittmer; Kathrin Sutter; George Kassiotis; Gennadiy Zelinskyy; Zoltán Bánki; Heribert Stoiber; Mario L Santiago; Kim J Hasenkrug
Journal:  FEMS Microbiol Rev       Date:  2019-09-01       Impact factor: 16.408

Review 8.  The Role of APOBECs in Viral Replication.

Authors:  Wendy Kaichun Xu; Hyewon Byun; Jaquelin P Dudley
Journal:  Microorganisms       Date:  2020-11-30

9.  Mouse APOBEC3 interferes with autocatalytic cleavage of murine leukemia virus Pr180gag-pol precursor and inhibits Pr65gag processing.

Authors:  Yoshiyuki Hakata; Jun Li; Takahiro Fujino; Yuki Tanaka; Rie Shimizu; Masaaki Miyazawa
Journal:  PLoS Pathog       Date:  2019-12-12       Impact factor: 6.823

Review 10.  Mouse APOBEC3 Restriction of Retroviruses.

Authors:  Karen Salas-Briceno; Wenming Zhao; Susan R Ross
Journal:  Viruses       Date:  2020-10-27       Impact factor: 5.048
  10 in total

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