Literature DB >> 24719072

Update on antibacterial soaps: the FDA takes a second look at triclosans.

Kendra Gail Bergstrom.   

Abstract

In December of 2013 the Food and Drug Administration announced it would look further into the safety and efficacy of the biocide triclosan and requested further safety data as part of a new review with the Environmental Protection Agency. The use of triclosan has increased exponentially since its introduction in in 1972, to the point that 75% of commercial soap brands contain triclosan and 76% of a nationwide sample of adults and children excrete triclosan in the urine. This announcement raised an important dialog about the appropriate use of all over the counter biocides. Particular concerns include whether these biocides are more effective than regular soaps, whether they may create new drug resistant bacteria, and whether they may also act as hormone disruptors in humans or the environment.

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Year:  2014        PMID: 24719072

Source DB:  PubMed          Journal:  J Drugs Dermatol        ISSN: 1545-9616            Impact factor:   2.114


  2 in total

1.  Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish.

Authors:  Derik E Haggard; Pamela D Noyes; Katrina M Waters; Robert L Tanguay
Journal:  Toxicol Appl Pharmacol       Date:  2016-08-15       Impact factor: 4.219

2.  Comparison of Transcriptomics Changes Induced by TCS and MTCS Exposure in Human Hepatoma HepG2 Cells.

Authors:  Xiaoqian Li; Yu Shang; Weiwei Yao; Yi Li; Ning Tang; Jing An; Yongjie Wei
Journal:  ACS Omega       Date:  2020-05-06
  2 in total

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