Literature DB >> 24718509

[Dark nail: clinical findings, diagnostics and therapy of melanonychia].

C Löser1, P A Mayser.   

Abstract

BACKGROUND: A dark colored pigmentation of nails can be due to a subungual malignant melanoma. There are, however, many other benign causes and this differentiation is an important challenge in dermatological practice. PROBLEM: When should nail pigmentation be clarified by histological investigations?
MATERIAL AND METHODS: This article gives a survey of the literature on this topic and a review of own experiences with clinical case examples. The various causes of melanonychia are presented and criteria for the early recognition of melanoma of the nail matrix are formulated.
RESULTS: The width and depth of color of longitudinal melanonychia do not allow any conclusions on the dignity. If the nail striation is proximally broader than distally, this is evidence of a proliferative event. Confirmation of a subungual hemorrhage does not exclude a malignancy per se. Also detection of pigmentation due to fungi does not exclude the additional presence of a subungual melanoma. A systematic clinical analysis using clear criteria leads to a working diagnosis and suitable treatment.
CONCLUSION: An early and correct designation of nail pigmentation can avoid unnecessary nail interventions but can also be life saving.

Entities:  

Mesh:

Year:  2014        PMID: 24718509     DOI: 10.1007/s00105-013-2706-y

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  13 in total

1.  Longitudinal melanonychia caused by Fusarium oxysporum in immunocompetent patient.

Authors:  Kui Young Park; Jin Woong Lee; In Su Kim; Moo Kyu Suh; Jong Soo Choi; Nam Ju Moon; Seong Jun Seo
Journal:  Mycoses       Date:  2011-11-11       Impact factor: 4.377

2.  Fungal melanonychia due to Candida albicans.

Authors:  Eujin Cho; Young Bok Lee; Hyun Jeong Park; Baik Kee Cho
Journal:  Int J Dermatol       Date:  2012-02-09       Impact factor: 2.736

Review 3.  Longitudinal melanonychia.

Authors:  E Haneke; R Baran
Journal:  Dermatol Surg       Date:  2001-06       Impact factor: 3.398

4.  Subungual Bowen disease revealed by longitudinal melanonychia.

Authors:  Tomoko Saito; Hiroshi Uchi; Yoichi Moroi; Hiromaro Kiryu; Masutaka Furue
Journal:  J Am Acad Dermatol       Date:  2012-11       Impact factor: 11.527

Review 5.  The ABC rule for clinical detection of subungual melanoma.

Authors:  E K Levit; M H Kagen; R K Scher; M Grossman; E Altman
Journal:  J Am Acad Dermatol       Date:  2000-02       Impact factor: 11.527

6.  Melanogenesis in dermatophyte species in vitro and during infection.

Authors:  Sirida Youngchim; Soraya Pornsuwan; Joshua D Nosanchuk; Wiyada Dankai; Nongnuch Vanittanakom
Journal:  Microbiology (Reading)       Date:  2011-05-12       Impact factor: 2.777

7.  [Onychomycosis with onychodystrophy or acrolentiginous melanoma with onychomycosis and onychodystrophy?].

Authors:  A Blum
Journal:  Hautarzt       Date:  2012-04       Impact factor: 0.751

Review 8.  Fungal melanonychia.

Authors:  Justin Finch; Roberto Arenas; Robert Baran
Journal:  J Am Acad Dermatol       Date:  2012-01-17       Impact factor: 11.527

Review 9.  Longitudinal melanonychia (melanonychia striata): diagnosis and management.

Authors:  R Baran; P Kechijian
Journal:  J Am Acad Dermatol       Date:  1989-12       Impact factor: 11.527

10.  Melanonychia.

Authors:  Julie Jefferson; Phoebe Rich
Journal:  Dermatol Res Pract       Date:  2012-06-27
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  1 in total

1.  [Allways an important subject : Diagnosis and treatment of nail diseases].

Authors:  Christoph R Löser
Journal:  Hautarzt       Date:  2018-09       Impact factor: 0.751

  1 in total

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