| Literature DB >> 2471694 |
K L Elkins1, P W Stashak, P J Baker.
Abstract
Prior exposure (priming) of BALB/cByJ mice to a low dose of lipopolysaccharide derived from Escherichia coli 055 or Serratia marcescens, followed by immunization with an optimally immunogenic dose of the same lipopolysaccharide 2 to 30 days later, results in the expression of substantially reduced antibody responses. Such unresponsiveness, which is antigen specific, occurs in a cyclic manner with time after priming.Entities:
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Year: 1989 PMID: 2471694 PMCID: PMC313869 DOI: 10.1128/iai.57.7.2253-2255.1989
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441