[Hepatoid adenocarcinoma of the stomach].

Hepatoid adenocarcinoma of the stomach is a gastric cancer with both adenocarcinoma and hepatocellular differentiation. It usually produces large amounts of alpha-fetoprotein (AFP). This carcinoma often occurs in the aged and commonly in the antrum. The prognosis is poor because of frequent liver metastasis. In the cytoplasm of the tumor cells, various serum proteins were identified, such as AFP, alpha-I antitrypsin (AAT) and alpha-I antichymotrypsin (ACT). Adenocarcinomatous foci were composed of well-differentiated intestinal type epithelial cells and often contained carcinoembryonic antigen (CEA).