Jun Wu1, Yu Li, Yong Cao, Shuo Wang. 1. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng district, 100050, Beijing, China.
Abstract
MATERIAL AND METHODS: The pathogenesis of cerebral arteriovenous malformations (cAVMs) is still not well understood. Generally, cAVMs are thought to be congenital lesions originating prenatally. We report a 7-year-old boy diagnosed with a de novo cAVM after 3 years of recurrent epileptic seizures. RESULTS: MR imaging at 4 years of age was normal. Follow-up MR imaging 3 years later demonstrated a de novo 2-cm cAVM in the right occipital lobe, confirmed by conventional angiography. We reviewed five previously reported cases of de novo cAVMs who did not have a previous neurovascular abnormality. Including our case, recurrent epileptic seizures are the major presentation (83.3 %) before de novo cAVM occurrence. CONCLUSION: We suggest that epileptic seizure is a potential trigger of de novo cAVMs.
MATERIAL AND METHODS: The pathogenesis of cerebral arteriovenous malformations (cAVMs) is still not well understood. Generally, cAVMs are thought to be congenital lesions originating prenatally. We report a 7-year-old boy diagnosed with a de novo cAVM after 3 years of recurrent epileptic seizures. RESULTS: MR imaging at 4 years of age was normal. Follow-up MR imaging 3 years later demonstrated a de novo 2-cm cAVM in the right occipital lobe, confirmed by conventional angiography. We reviewed five previously reported cases of de novo cAVMs who did not have a previous neurovascular abnormality. Including our case, recurrent epileptic seizures are the major presentation (83.3 %) before de novo cAVM occurrence. CONCLUSION: We suggest that epilepticseizure is a potential trigger of de novo cAVMs.
Authors: Tomoki Hashimoto; Michael T Lawton; Gen Wen; Guo-Yuan Yang; Thomas Chaly; Campbell L Stewart; Holly K Dressman; Nicholas M Barbaro; Douglas A Marchuk; William L Young Journal: Neurosurgery Date: 2004-02 Impact factor: 4.654