Ashley Levan1, Leslie Baxter, C Brock Kirwan, Garrett Black, Shawn D Gale. 1. Department of Psychology (Messrs Levan and Black and Drs Kirwan, and Gale) and The Neuroscience Center (Drs Kirwan and Gale), Brigham Young University, Provo, Utah; and Department of Neuroimaging, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona (Dr Baxter).
Abstract
OBJECTIVE: To examine the association between right frontal pole cortical thickness, social competence, and cognitive proficiency in children participants with a history of chronic traumatic brain injury (TBI). PARTICIPANTS: Twenty-three children (65% male; M age = 12.8 years, SD = 2.3 years) at least 1 year post-injury (M = 3.3 years, SD = 1.7 years) were evaluated with the Cognitive Proficiency Index (CPI) from the Wechsler Intelligence Scale for Children, 4th Edition, and their caregiver completed the Child Behavior Checklist. Social competence was evaluated with the Social Competence and Social Problems subscales from the Child Behavior Checklist. Right frontal pole cortical thickness was calculated via FreeSurfer from high-resolution 3-dimensional T1 magnetic resonance imaging scans. RESULTS: Direct effect of right frontal pole cortical thickness on social competence was significant (β = 14.09, SE = 4.6, P < .01). Right frontal pole cortical thickness significantly predicted CPI (β = 18.44, SE = 4.9, P < .05), and CPI significantly predicted social competence (β = 0.503, SE = 0.17, P < .01). Findings were consistent with the hypothesized mediation model. CONCLUSIONS: The association between right frontal lobe cortical integrity and social competence in pediatric participants with chronic TBI may be mediated through cognitive proficiency.
OBJECTIVE: To examine the association between right frontal pole cortical thickness, social competence, and cognitive proficiency in childrenparticipants with a history of chronic traumatic brain injury (TBI). PARTICIPANTS: Twenty-three children (65% male; M age = 12.8 years, SD = 2.3 years) at least 1 year post-injury (M = 3.3 years, SD = 1.7 years) were evaluated with the Cognitive Proficiency Index (CPI) from the Wechsler Intelligence Scale for Children, 4th Edition, and their caregiver completed the Child Behavior Checklist. Social competence was evaluated with the Social Competence and Social Problems subscales from the Child Behavior Checklist. Right frontal pole cortical thickness was calculated via FreeSurfer from high-resolution 3-dimensional T1 magnetic resonance imaging scans. RESULTS: Direct effect of right frontal pole cortical thickness on social competence was significant (β = 14.09, SE = 4.6, P < .01). Right frontal pole cortical thickness significantly predicted CPI (β = 18.44, SE = 4.9, P < .05), and CPI significantly predicted social competence (β = 0.503, SE = 0.17, P < .01). Findings were consistent with the hypothesized mediation model. CONCLUSIONS: The association between right frontal lobe cortical integrity and social competence in pediatric participants with chronic TBI may be mediated through cognitive proficiency.
Authors: Curt A Sandman; Megan M Curran; Elysia Poggi Davis; Laura M Glynn; Kevin Head; Tallie Z Baram Journal: Am J Psychiatry Date: 2018-03-02 Impact factor: 18.112
Authors: Marie-Stephanie Cahart; Ali Amad; Stephen B Draper; Ruth G Lowry; Luigi Marino; Cornelia Carey; Cedric E Ginestet; Marcus S Smith; Steven C R Williams Journal: Proc Natl Acad Sci U S A Date: 2022-05-31 Impact factor: 12.779