Masahiro Yanagawa1, Tomoko Gyobu2, Ann N Leung3, Misa Kawai2, Yutaka Kawata4, Hiromitsu Sumikawa2, Osamu Honda2, Noriyuki Tomiyama2. 1. Department of Diagnostic Radiology, Stanford University School of Medicine, 1201 Welch Rd, Stanford, CA 94305; Department of Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. Electronic address: masayana@stanford.edu. 2. Department of Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. 3. Department of Diagnostic Radiology, Stanford University School of Medicine, 1201 Welch Rd, Stanford, CA 94305. 4. Department of Radiology, Osaka Rosai Hospital, Sakai, Osaka, Japan.
Abstract
RATIONALE AND OBJECTIVES: To compare quality of ultra-low-dose thin-section computed tomography (CT) images of the lung reconstructed using model-based iterative reconstruction (MBIR) and adaptive statistical iterative reconstruction (ASIR) to filtered back projection (FBP) and to determine the minimum tube current-time product on MBIR images by comparing to standard-dose FBP images. MATERIALS AND METHODS: Ten cadaveric lungs were scanned using 120 kVp and four different tube current-time products (8, 16, 32, and 80 mAs). Thin-section images were reconstructed using MBIR, three ASIR blends (30%, 60%, and 90%), and FBP. Using the 8-mAs data, side-to-side comparison of the four iterative reconstruction image sets to FBP was performed by two independent observers who evaluated normal and abnormal findings, subjective image noise, streak artifact, and overall image quality. Image noise was also measured quantitatively. Subsequently, 8-, 16-, and 32-mAs MBIR images were compared to standard-dose FBP images. Comparisons of image sets were analyzed using the Wilcoxon signed rank test with Bonferroni correction. RESULTS: At 8 mAs, MBIR images were significantly better (P < .005) than other reconstruction techniques except in evaluation of interlobular septal thickening. Each set of low-dose MBIR images had significantly lower (P < .001) subjective and objective noise and streak artifacts than standard-dose FBP images. Conspicuity and visibility of normal and abnormal findings were not significantly different between 16-mAs MBIR and 80-mAs FBP images except in identification of intralobular reticular opacities. CONCLUSIONS: MBIR imaging shows higher overall quality with lower noise and streak artifacts than ASIR or FBP imaging, resulting in nearly 80% dose reduction without any degradations of overall image quality.
RATIONALE AND OBJECTIVES: To compare quality of ultra-low-dose thin-section computed tomography (CT) images of the lung reconstructed using model-based iterative reconstruction (MBIR) and adaptive statistical iterative reconstruction (ASIR) to filtered back projection (FBP) and to determine the minimum tube current-time product on MBIR images by comparing to standard-dose FBP images. MATERIALS AND METHODS: Ten cadaveric lungs were scanned using 120 kVp and four different tube current-time products (8, 16, 32, and 80 mAs). Thin-section images were reconstructed using MBIR, three ASIR blends (30%, 60%, and 90%), and FBP. Using the 8-mAs data, side-to-side comparison of the four iterative reconstruction image sets to FBP was performed by two independent observers who evaluated normal and abnormal findings, subjective image noise, streak artifact, and overall image quality. Image noise was also measured quantitatively. Subsequently, 8-, 16-, and 32-mAs MBIR images were compared to standard-dose FBP images. Comparisons of image sets were analyzed using the Wilcoxon signed rank test with Bonferroni correction. RESULTS: At 8 mAs, MBIR images were significantly better (P < .005) than other reconstruction techniques except in evaluation of interlobular septal thickening. Each set of low-dose MBIR images had significantly lower (P < .001) subjective and objective noise and streak artifacts than standard-dose FBP images. Conspicuity and visibility of normal and abnormal findings were not significantly different between 16-mAs MBIR and 80-mAs FBP images except in identification of intralobular reticular opacities. CONCLUSIONS: MBIR imaging shows higher overall quality with lower noise and streak artifacts than ASIR or FBP imaging, resulting in nearly 80% dose reduction without any degradations of overall image quality.
Authors: Debra Boyer; Mary Nevin; Carey C Thomson; Don B Sanders; Stamatia Alexiou; Samuel B Goldfarb; Jennifer L Nicholas; Paul G Thacker; Andrea M Coverstone; Albert Faro; George Cheng; Adnan Majid; Paul E Moore Journal: Ann Am Thorac Soc Date: 2015-11
Authors: K A Shpilberg; B N Delman; L N Tanenbaum; S J Esses; R Subramaniam; A H Doshi Journal: AJNR Am J Neuroradiol Date: 2014-07-17 Impact factor: 3.825