Literature DB >> 24711959

Tumor-infiltrating lymphocytes favor the response to chemoradiotherapy of head and neck cancer.

Panagiotis Balermpas1, Franz Rödel1, Christian Weiss1, Claus Rödel1, Emmanouil Fokas1.   

Abstract

Tumor-infiltrating lymphocytes (TILs) play an important role in the response of neoplastic lesions to therapy. We have recently shown that a robust tumor infiltration by CD3+ and CD8+ T cells correlates with improved disease outcome upon definitive chemoradiotherapy in patients with head and neck cancer, in a manner that is influenced by tumor compartment and human papilloma virus status. Our data highlight the prognostic and therapeutic relevance of TILs in head and neck cancer.

Entities:  

Keywords:  HPV; head and neck cancer; prognostic value; radiotherapy; tumor infiltrating lymphocytes

Year:  2014        PMID： 24711959      PMCID： PMC3976983          DOI： 10.4161/onci.27403

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

1.  Human papillomavirus and survival of patients with oropharyngeal cancer.

Authors:  K Kian Ang; Jonathan Harris; Richard Wheeler; Randal Weber; David I Rosenthal; Phuc Felix Nguyen-Tân; William H Westra; Christine H Chung; Richard C Jordan; Charles Lu; Harold Kim; Rita Axelrod; C Craig Silverman; Kevin P Redmond; Maura L Gillison
Journal:  N Engl J Med       Date:  2010-06-07       Impact factor: 91.245

Review 2.  Cancer immunotherapy--revisited.

Authors:  W Joost Lesterhuis; John B A G Haanen; Cornelis J A Punt
Journal:  Nat Rev Drug Discov       Date:  2011-08-01       Impact factor: 84.694

Review 3.  Radiation as an immune modulator.

Authors:  Byron Burnette; Ralph R Weichselbaum
Journal:  Semin Radiat Oncol       Date:  2013-10       Impact factor: 5.934

Review 4.  Harnessing the immune system to treat cancer.

Authors:  Nina Bhardwaj
Journal:  J Clin Invest       Date:  2007-05       Impact factor: 14.808

5.  The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas.

Authors:  Christina S Kong; Balasubramanian Narasimhan; Hongbin Cao; Shirley Kwok; Julianna P Erickson; Albert Koong; Nader Pourmand; Quynh-Thu Le
Journal:  Int J Radiat Oncol Biol Phys       Date:  2009-06-01       Impact factor: 7.038

Review 6.  Head and neck cancer.

Authors:  Athanassios Argiris; Michalis V Karamouzis; David Raben; Robert L Ferris
Journal:  Lancet       Date:  2008-05-17       Impact factor: 79.321

7.  Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer.

Authors:  Carsten Denkert; Sibylle Loibl; Aurelia Noske; Marc Roller; Berit Maria Müller; Martina Komor; Jan Budczies; Silvia Darb-Esfahani; Ralf Kronenwett; Claus Hanusch; Christian von Törne; Wilko Weichert; Knut Engels; Christine Solbach; Iris Schrader; Manfred Dietel; Gunter von Minckwitz
Journal:  J Clin Oncol       Date:  2009-11-16       Impact factor: 44.544

8.  CD8+ and CD4+ tumour infiltrating lymphocytes in relation to human papillomavirus status and clinical outcome in tonsillar and base of tongue squamous cell carcinoma.

Authors:  Cecilia Nordfors; Nathalie Grün; Nikolaos Tertipis; Andreas Ährlund-Richter; Linnea Haeggblom; Lars Sivars; Juan Du; Tommy Nyberg; Linda Marklund; Eva Munck-Wikland; Anders Näsman; Torbjörn Ramqvist; Tina Dalianis
Journal:  Eur J Cancer       Date:  2013-04-06       Impact factor: 9.162

Review 9.  The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis.

Authors:  M J M Gooden; G H de Bock; N Leffers; T Daemen; H W Nijman
Journal:  Br J Cancer       Date:  2011-05-31       Impact factor: 7.640

10.  Tumour-infiltrating lymphocytes predict response to definitive chemoradiotherapy in head and neck cancer.

Authors:  P Balermpas; Y Michel; J Wagenblast; O Seitz; C Weiss; F Rödel; C Rödel; E Fokas
Journal:  Br J Cancer       Date:  2013-10-15       Impact factor: 7.640
  10 in total
  28 in total

1.  Irradiation enhances dendritic cell potential antitumor activity by inducing tumor cell expressing TNF-α.

Authors:  Lijia Chang; Zhengzheng Zhang; Fang Chen; Wen Zhang; Shuang Song; Shuxia Song
Journal:  Med Oncol       Date:  2017-02-13       Impact factor: 3.064

2.  Two immune-enhanced molecular subtypes differ in inflammation, checkpoint signaling and outcome of advanced head and neck squamous cell carcinoma.

Authors:  Bangrong Cao; Qifeng Wang; Huan Zhang; Guiquan Zhu; Jinyi Lang
Journal:  Oncoimmunology       Date:  2017-11-06       Impact factor: 8.110

3.  Kv1.3 Channels Mark Functionally Competent CD8+ Tumor-Infiltrating Lymphocytes in Head and Neck Cancer.

Authors:  Ameet A Chimote; Peter Hajdu; Alexandros M Sfyris; Brittany N Gleich; Trisha Wise-Draper; Keith A Casper; Laura Conforti
Journal:  Cancer Res       Date:  2016-11-04       Impact factor: 12.701

Review 4.  Telltale tumor infiltrating lymphocytes (TIL) in oral, head & neck cancer.

Authors:  Yu Lei; Yuying Xie; Yee Sun Tan; Mark E Prince; Jeffrey S Moyer; Jacques Nör; Gregory T Wolf
Journal:  Oral Oncol       Date:  2016-08-21       Impact factor: 5.337

Review 5.  Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.

Authors:  Aitziber Buqué; Norma Bloy; Fernando Aranda; Isabelle Cremer; Alexander Eggermont; Wolf Hervé Fridman; Jitka Fucikova; Jérôme Galon; Radek Spisek; Eric Tartour; Laurence Zitvogel; Guido Kroemer; Lorenzo Galluzzi
Journal:  Oncoimmunology       Date:  2016-03-10       Impact factor: 8.110

6.  Effects of Tobacco Smoking on the Tumor Immune Microenvironment in Head and Neck Squamous Cell Carcinoma.

Authors:  Janis V de la Iglesia; Robbert J C Slebos; Laura Martin-Gomez; Xuefeng Wang; Jamie K Teer; Aik Choon Tan; Travis A Gerke; Garrick Aden-Buie; Tessa van Veen; Jude Masannat; Ritu Chaudhary; Feifei Song; Michelle Fournier; Erin M Siegel; Matthew B Schabath; J Trad Wadsworth; Jimmy Caudell; Louis Harrison; Bruce M Wenig; Jose Conejo-Garcia; Juan C Hernandez-Prera; Christine H Chung
Journal:  Clin Cancer Res       Date:  2019-12-17       Impact factor: 12.531

Review 7.  Checkpoint immunotherapy in head and neck cancers.

Authors:  Paul Zolkind; Ravindra Uppaluri
Journal:  Cancer Metastasis Rev       Date:  2017-09       Impact factor: 9.264

8.  Prognostic significance of the lymphocyte-to-monocyte ratio in patients with small cell lung cancer.

Authors:  Se-Il Go; Rock Bum Kim; Haa-Na Song; Myoung Hee Kang; Un Seok Lee; Hye Jung Choi; Seung Jun Lee; Yu Ji Cho; Yi Yeong Jeong; Ho Cheol Kim; Jong Deog Lee; Seok-Hyun Kim; Jung-Hun Kang; Hui Ling; Gyeong-Won Lee
Journal:  Med Oncol       Date:  2014-11-23       Impact factor: 3.064

9.  Tumor infiltrating lymphocytes (TILs) before and after neoadjuvant chemoradiotherapy and its clinical utility for rectal cancer.

Authors:  Feifei Teng; Dianbin Mu; Xiangjiao Meng; Li Kong; Hui Zhu; Sujing Liu; Jianbo Zhang; Jinming Yu
Journal:  Am J Cancer Res       Date:  2015-05-15       Impact factor: 6.166

10.  A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment.

Authors:  Ameet A Chimote; Andras Balajthy; Michael J Arnold; Hannah S Newton; Peter Hajdu; Julianne Qualtieri; Trisha Wise-Draper; Laura Conforti
Journal:  Sci Signal       Date:  2018-04-24       Impact factor: 8.192
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.