Katherine Sullivan1, Cecilia M Shikuma2, Dominic Chow2, Elizabeth Cornelius1, Rebecca K Romine1, Rachel A Lindsey3, Christopher D Stickley1, Iris F Kimura1, Ronald K Hetzler1. 1. Department of Kinesiology and Rehabilitation Science, College of Education, University of Hawaii - Manoa, Honolulu, Hawaii. 2. Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii. 3. Department of Kinesiology and Rehabilitation Science, College of Education, University of Hawaii - Manoa, Honolulu, Hawaii Department of Sports Medicine, West Chester University, West Chester, Pennsylvania.
Abstract
BACKGROUND: Non-exercise (N-EX) questionnaires have been developed to determine maximal oxygen consumption (VO2max) in healthy populations. There are limited reliable and validated N-EX questionnaires for the HIV+ population that provide estimates of habitual physical activity and not VO2max. OBJECTIVES: To determine how well regression equations developed previously on healthy populations, including N-EX prediction equations for VO2max and age-predicted maximal heart rates (APMHR), worked on an HIV+ population; and to develop a specific N-EX prediction equation for VO2max and APMHR for HIV+ individuals. METHODS: Sixty-six HIV+ participants on stable HAART completed 4 N-EX questionnaires and performed a maximal graded exercise test. RESULTS: Sixty males and 6 females were included; mean (SD) age was 49.2 (8.2) years; CD4 count was 516.0 ± 253.0 cells·mm-3; and 92% had undetectable HIV PCR. Mean VO2max was 29.2 ± 7.6 (range, 14.4-49.4) mL·kg-1·min-1 Despite positive correlations with VO2max, previously published N-EX VO2max equations produced results significantly different than actual VO2 scores (P < .0001). An HIV+ specific N-EX equation was developed and produced similar mean VO2max values, R = 0.71, when compared to achieved VO2max (P = .53). CONCLUSION: HIV+ individuals tend to be sedentary and unfit, putting them at increased risk for the development of chronic diseases associated with a sedentary lifestyle. Based on the level of error associated with utilizing APMHR and N-EX VO2max equations with HIV+ individuals, neither should be used in this population for exercise prescription.
BACKGROUND: Non-exercise (N-EX) questionnaires have been developed to determine maximal oxygen consumption (VO2max) in healthy populations. There are limited reliable and validated N-EX questionnaires for the HIV+ population that provide estimates of habitual physical activity and not VO2max. OBJECTIVES: To determine how well regression equations developed previously on healthy populations, including N-EX prediction equations for VO2max and age-predicted maximal heart rates (APMHR), worked on an HIV+ population; and to develop a specific N-EX prediction equation for VO2max and APMHR for HIV+ individuals. METHODS: Sixty-six HIV+ participants on stable HAART completed 4 N-EX questionnaires and performed a maximal graded exercise test. RESULTS: Sixty males and 6 females were included; mean (SD) age was 49.2 (8.2) years; CD4 count was 516.0 ± 253.0 cells·mm-3; and 92% had undetectable HIV PCR. Mean VO2max was 29.2 ± 7.6 (range, 14.4-49.4) mL·kg-1·min-1 Despite positive correlations with VO2max, previously published N-EX VO2max equations produced results significantly different than actual VO2 scores (P < .0001). An HIV+ specific N-EX equation was developed and produced similar mean VO2max values, R = 0.71, when compared to achieved VO2max (P = .53). CONCLUSION: HIV+ individuals tend to be sedentary and unfit, putting them at increased risk for the development of chronic diseases associated with a sedentary lifestyle. Based on the level of error associated with utilizing APMHR and N-EX VO2max equations with HIV+ individuals, neither should be used in this population for exercise prescription.
Authors: W T Cade; D N Reeds; S Lassa-Claxton; V G Davila-Roman; A D Waggoner; W G Powderly; K E Yarasheski Journal: HIV Med Date: 2007-12-18 Impact factor: 3.180
Authors: Soula Fillipas; Flavia Cicuttini; Anne Elizabeth Holland; Catherine L Cherry Journal: J Assoc Nurses AIDS Care Date: 2010-01-29 Impact factor: 1.354
Authors: Carol Ewing Garber; Bryan Blissmer; Michael R Deschenes; Barry A Franklin; Michael J Lamonte; I-Min Lee; David C Nieman; David P Swain Journal: Med Sci Sports Exerc Date: 2011-07 Impact factor: 5.411
Authors: Ronald L Gellish; Brian R Goslin; Ronald E Olson; Audry McDonald; Gary D Russi; Virinder K Moudgil Journal: Med Sci Sports Exerc Date: 2007-05 Impact factor: 5.411
Authors: Gregory A Hand; Kenneth D Phillips; Wesley D Dudgeon; G William Lyerly; J Larry Durstine; Stephanie E Burgess Journal: AIDS Care Date: 2008-10
Authors: Ronald K Hetzler; Christopher D Stickley; Cecilia M Shikuma; Dominic Chow; Courtney E Takahashi; Iris F Kimura; Alexis T Barnett Journal: HIV Clin Trials Date: 2009 Jul-Aug