Guido Filler1, Bernd Hoppe. 1. Department of Paediatrics, Schulich School of Medicine & Dentistry, London, ON, N6A 5W9, Canada; Department of Medicine, Schulich School of Medicine & Dentistry, London, ON, N6A 5W9, Canada; Department of Pathology and Laboratory Medicine, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, N5A 5A5, Canada. guido.filler@lhsc.on.ca.