Literature DB >> 24707606

[Origin of surgical metastatic bone disease].

L J Sánchez-Torres, A Ruiz-Tenorio, M M Chávez-Reyna, E A Rodríguez-Domínguez, O Rascón-Alvarez, M Santos-Hernández.   

Abstract

BACKGROUND: Metastatic bone disease should be considered as a public health problem. The alterations it may cause include pain that is refractory to medical treatment, metabolic instability, pathologic fractures and spinal disorders.
MATERIAL AND METHODS: The primary tumor site that led to the need for surgery was investigated in a series of patients with a diagnosis of metastatic bone disease. The bone involved and the histology of the lesions were also studied.
RESULTS: Kidney cancer was the one that most frequently required a surgical procedure; it was followed by breast and prostate cancer. The primary tumor was not found in 6.36% of cases. The bones affected by the lesions studied were as follows in order of occurrence: femur, spine, humerus and pelvis. Adenocarcinoma was the most frequent histological diagnosis. DISCUSSION: The diagnosis of metastatic bone disease should always be considered in patients over forty years of age with skeletal lesions, preferably lytic.
CONCLUSIONS: In this study, kidney cancer, the proximal limbs and adenocarcinomas were the variables that most frequently produced metastatic bone lesions that warranted a surgical procedure.

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Year:  2013        PMID: 24707606

Source DB:  PubMed          Journal:  Acta Ortop Mex        ISSN: 2306-4102


  1 in total

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Authors:  Hongjing Cui; Huican Zhang; Deng Pan; Bing Zhao
Journal:  J Environ Public Health       Date:  2022-09-10
  1 in total

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