Literature DB >> 24705190

Pigmented villous nodular synovitis mimicking metastatic melanoma on PET-CT.

Luke Selby1, Moshim Kukar2, John Wang3, Mansoor Beg3, James Sullivan3.   

Abstract

INTRODUCTION: Positron Emission Tomography - Computed Tomography (PET-CT) is routinely utilized in the management of melanoma, either as a part of staging workup or during surveillance. Since melanomas have a high metastatic potential, any FDG avid lesion is considered suspicious for recurrence. We report a case of a FDG avid lesion, diagnosed during melanoma surveillance, its management and review of literature. PRESENTATION OF CASE: A 58 year-old-male underwent wide local excision for melanoma of the left cheek, and one year post-operatively a PET-CT that revealed a hypermetabolic focus in his right subscapularis muscle, which upon resection was diagnosed as Pigmented Villonodular Synovitis (PVNS). DISCUSSION: PVNS is a rare benign giant cell tumor that requires no additional treatment in asymptomatic individuals. PET-CT is used for staging and surveillance of numerous malignancies, including melanoma. A hypermetabolic lesion on a PET-CT scan in the setting of malignancy is always suspicious for recurrence.
CONCLUSION: The surgeon is reminded of a uncommon benign FDG avid lesion. Typical location, nonspecific symptoms and characteristic imaging findings help cue in the diagnosis of PVNS and a tissue diagnosis will establish the diagnosis, thus avoiding unnecessarily aggressive surgical management.
Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Metastatic melanoma; Pigmented villous nodular synovitis

Year:  2014        PMID: 24705190      PMCID: PMC4008855          DOI: 10.1016/j.ijscr.2014.02.009

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  4 in total

Review 1.  Pigmented villonodular synovitis.

Authors:  Wakenda K Tyler; Armando F Vidal; Riley J Williams; John H Healey
Journal:  J Am Acad Orthop Surg       Date:  2006-06       Impact factor: 3.020

2.  Localized nodular synovitis mimicking metastatic melanoma in a patient with metastatic melanoma on whole-body F-18 FDG PET/CT with MRI and pathological correlation.

Authors:  Syed Mahmood; Sofia R Martínez de Llano
Journal:  Clin Nucl Med       Date:  2007-07       Impact factor: 7.794

3.  Extensive pigmented villonodular synovitis with markedly pigmented lymphadenopathy and its implication for differential diagnosis with malignant melanoma.

Authors:  Sijian Wang; John M Stewart; Merrick I Ross; Victor G Prieto
Journal:  Ann Diagn Pathol       Date:  2003-04       Impact factor: 2.090

4.  Incidental detection of pigmented villonodular synovitis on FDG PET.

Authors:  Mehmet T Kitapci; R Edward Coleman
Journal:  Clin Nucl Med       Date:  2003-08       Impact factor: 7.794

  4 in total
  4 in total

1.  Successful treatment of a diffuse type tenosynovial giant cell tumor in the thoracic spine mimicking spinal metastasis by frozen recapping laminoplasty in a patient with thyroid cancer.

Authors:  Noritaka Yonezawa; Hideki Murakami; Satoshi Kato; Hiroyuki Hayashi; Hiroyuki Tsuchiya
Journal:  Eur Spine J       Date:  2018-04-16       Impact factor: 3.134

2.  Pigmented Villonodular Synovitis: A Close Mimic of Metastasis on 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography.

Authors:  Kunal Shaha; Archi Agrawal; Neha Mittal; Nilendu Purandare; Umesh Mahantshetty; Sneha Shah; Amey Puranik; Venkatesh Rangarajan
Journal:  Indian J Nucl Med       Date:  2018 Jan-Mar

3.  Chronic lymphoplasmacytic villonodular proliferative synovitis in a 10-year-old Jack Russell Terrier dog.

Authors:  Tafara Mapuvire; Erick Kandiwa; Pricilla Mbiri; Alaster Samkange; Oscar Madzingira; Borden Mushonga
Journal:  Int J Vet Sci Med       Date:  2020-11-18

4.  Tenosynovial giant cell tumors in unusual locations detected by positron emission tomography imaging confused with malignant tumors: report of two cases.

Authors:  Akihiko Takeuchi; Norio Yamamoto; Katsuhiro Hayashi; Shinji Miwa; Masayuki Takahira; Kiyokazu Fukui; Taku Oikawa; Hiroyuki Tsuchiya
Journal:  BMC Musculoskelet Disord       Date:  2016-04-26       Impact factor: 2.362

  4 in total

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