Literature DB >> 24705167

In vivo study of chitosan-natural nano hydroxyapatite scaffolds for bone tissue regeneration.

Jong Seo Lee1, Sang Dae Baek2, Jayachandran Venkatesan3, Ira Bhatnagar4, Hee Kyung Chang5, Hui Taek Kim6, Se-Kwon Kim7.   

Abstract

Significant development has been achieved with bioceramics and biopolymer scaffolds in the construction of artificial bone. In the present study, we have developed and compared chitosan-micro hydroxyapatite (chitosan-mHA) and chitosan-nano hydroxyapatite (chitosan-nHA) scaffolds as bone graft substitutes. The biocompatibility and cell proliferation of the prepared scaffolds were checked with preosteoblast (MC3T3-E1) cells. Total Volume (TV), bone volume (BV), bone surface (BS), trabecular thickness (Tb.Th), trabecular number (Tb.N) and trabecular separation (Tb.Sp) were found to be higher in chitosan-nHA than chitosan-mHA scaffold. Hence, we suggest that chitosan-nHA scaffold could be a promising biomaterial for bone tissue engineering.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Chitosan; Marine biomaterials; Natural hydroxyapatite

Mesh：

Substances：

Year:  2014        PMID： 24705167     DOI： 10.1016/j.ijbiomac.2014.03.053

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN： 0141-8130            Impact factor:   6.953


  15 in total

1.  Effect of enzymatic degradation of chitosan in polyhydroxybutyrate/chitosan/calcium phosphate composites on in vitro osteoblast response.

Authors:  Maria Giretova; Lubomir Medvecky; Radoslava Stulajterova; Tibor Sopcak; Jaroslav Briancin; Monika Tatarkova
Journal:  J Mater Sci Mater Med       Date:  2016-10-21       Impact factor: 3.896

2.  Improving the Mechanical Resistance of Hydroxyapatite/Chitosan Composite Materials Made of Nanofibers with Crystalline Preferential Orientation.

Authors:  Ricardo Pascual Alanis-Gómez; Eric Mauricio Rivera-Muñoz; Gabriel Luna-Barcenas; José Rafael Alanis-Gómez; Rodrigo Velázquez-Castillo
Journal:  Materials (Basel)       Date:  2022-07-05       Impact factor: 3.748

3.  Preparation, characterization, and in vitro osteoblast functions of a nano-hydroxyapatite/polyetheretherketone biocomposite as orthopedic implant material.

Authors:  Rui Ma; Songchao Tang; Honglue Tan; Wentao Lin; Yugang Wang; Jie Wei; Liming Zhao; Tingting Tang
Journal:  Int J Nanomedicine       Date:  2014-08-18

4.  Chitosan nanocomposites based on distinct inorganic fillers for biomedical applications.

Authors:  Duarte Moura; João F Mano; Maria C Paiva; Natália M Alves
Journal:  Sci Technol Adv Mater       Date:  2016-10-10       Impact factor: 8.090

5.  Influence of Parathyroid Hormone-Loaded PLGA Nanoparticles in Porous Scaffolds for Bone Regeneration.

Authors:  Piergiorgio Gentile; Vijay Kumar Nandagiri; Ritesh Pabari; Jacqueline Daly; Chiara Tonda-Turo; Gianluca Ciardelli; Zebunnissa Ramtoola
Journal:  Int J Mol Sci       Date:  2015-08-28       Impact factor: 5.923

6.  Bone regeneration by nanohydroxyapatite/chitosan/poly(lactide-co-glycolide) scaffolds seeded with human umbilical cord mesenchymal stem cells in the calvarial defects of the nude mice.

Authors:  Fei Wang; Xiao-Xia Su; Yu-Cheng Guo; Ang Li; Yin-Cheng Zhang; Hong Zhou; Hu Qiao; Li-Min Guan; Min Zou; Xin-Qin Si
Journal:  Biomed Res Int       Date:  2015-10-13       Impact factor: 3.411

Review 7.  Chitosan and Its Potential Use as a Scaffold for Tissue Engineering in Regenerative Medicine.

Authors:  Martin Rodríguez-Vázquez; Brenda Vega-Ruiz; Rodrigo Ramos-Zúñiga; Daniel Alexander Saldaña-Koppel; Luis Fernando Quiñones-Olvera
Journal:  Biomed Res Int       Date:  2015-10-04       Impact factor: 3.411

8.  Chitosan-Graphene Oxide 3D scaffolds as Promising Tools for Bone Regeneration in Critical-Size Mouse Calvarial Defects.

Authors:  Anca Hermenean; Ada Codreanu; Hildegard Herman; Cornel Balta; Marcel Rosu; Ciprian Valentin Mihali; Alexandra Ivan; Sorina Dinescu; Mariana Ionita; Marieta Costache
Journal:  Sci Rep       Date:  2017-11-30       Impact factor: 4.379

Review 9.  Versatility of Chitosan-Based Biomaterials and Their Use as Scaffolds for Tissue Regeneration.

Authors:  José Carlos Viana Ribeiro; Rodrigo Silveira Vieira; Iracema Matos Melo; Vilana Maria Adriano Araújo; Vilma Lima
Journal:  ScientificWorldJournal       Date:  2017-04-16

10.  Application of nano-hydroxyapatite/chitosan scaffolds on rat calvarial critical-sized defects: A pilot study.

Authors:  E Chatzipetros; P Christopoulos; C Donta; K-I Tosios; E Tsiambas; D Tsiourvas; E-M Kalogirou; K Tsiklakis
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2018-09-01
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