Literature DB >> 24704723

Childhood malnutrition and parasitic helminth interactions.

Keren Papier1, Gail M Williams2, Ruby Luceres-Catubig3, Faruk Ahmed1, Remigio M Olveda3, Donald P McManus4, Delia Chy5, Thao N P Chau6, Darren J Gray2, Allen G P Ross7.   

Abstract

BACKGROUND: There is evidence to support that nutritional deficiency can reduce the body's immune function, thereby decreasing resistance to disease and increasing susceptibility to intestinal parasites.
METHODS: A cross-sectional survey was carried out on 693 school-aged children from 5 schistosomiasis-endemic villages in Northern Samar, the Philippines. Data on dietary intake, nutritional status, and intestinal parasitic infection were collected.
RESULTS: The prevalence of stunting, thinness, and wasting was 49.2%, 27.8%, and 59.7% of all children. The proportion of children infected with Schistosoma japonicum (15.6%, P = .03) and hookworm (22.0%, P = .05) were significantly lower among children who met the recommended energy and nutrient intake (RENI) for total calories. The percentage of children infected with Trichuris trichiura was highest among children who did not meet the RENI for energy (74.1%, P = .04), iron (73.4%, P = .01), thiamine (74.0%, P = .00), and riboflavin (73.3%, P = .01). Susceptibility to having 1 or more parasitic infections was significantly associated with poor intake of energy (P = .04), thiamine (P = .02), and riboflavin (P = .01).The proportion of stunted children was significantly higher among children who did not meet the RENI for energy (68.9%, P = .002), protein (54.0%, P = .004), or niacin (30.8%, P = .02) and for those infected with hookworm (31.8%, P = .0002). After adjusting for potential confounders, protein intake less than the RENI (odds ratio [OR], 1.48; 95% confidence interval [CI], 1.03-2.14), and hookworm infection (OR, 1.77; 95% CI, 1.22-2.55) were the major predictors of stunting.
CONCLUSIONS: The results support the hypothesis that poor nutrient intake may increase susceptibility to parasitic diseases and together they negatively affect childhood nutritional status.
© The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  adolescents; childhood; intestinal parasites; malnutrition; schistosomiasis

Mesh:

Year:  2014        PMID: 24704723     DOI: 10.1093/cid/ciu211

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  38 in total

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Review 3.  Impact of Childhood Malnutrition on Host Defense and Infection.

Authors:  Marwa K Ibrahim; Mara Zambruni; Christopher L Melby; Peter C Melby
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Review 4.  The unusual suspects--innate lymphoid cells as novel therapeutic targets in IBD.

Authors:  Rimma Goldberg; Natalie Prescott; Graham M Lord; Thomas T MacDonald; Nick Powell
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5.  Identification of human intestinal parasites affecting an asymptomatic peri-urban Argentinian population using multi-parallel quantitative real-time polymerase chain reaction.

Authors:  Rubén O Cimino; Rebecca Jeun; Marisa Juarez; Pamela S Cajal; Paola Vargas; Adriana Echazú; Patricia E Bryan; Julio Nasser; Alejandro Krolewiecki; Rojelio Mejia
Journal:  Parasit Vectors       Date:  2015-07-17       Impact factor: 3.876

6.  Height, zinc and soil-transmitted helminth infections in schoolchildren: a study in Cuba and Cambodia.

Authors:  Brechje de Gier; Liliane Mpabanzi; Kim Vereecken; Suzanne D van der Werff; Patrick C D'Haese; Marion Fiorentino; Kuong Khov; Marlene Perignon; Chhoun Chamnan; Jacques Berger; Megan E Parker; Raquel Junco Díaz; Fidel Angel Núñez; Lázara Rojas Rivero; Mariano Bonet Gorbea; Colleen M Doak; Maiza Campos Ponce; Frank T Wieringa; Katja Polman
Journal:  Nutrients       Date:  2015-04-20       Impact factor: 5.717

7.  Evaluation of biochemical, hematological and parasitological parameters of protein-deficient hamsters infected with Ancylostoma ceylanicum.

Authors:  Carina P Pacanaro; Sílvia R Dias; Luciana R Serafim; Mariana P Costa; Edenil Aguilar; Paulo R Paes; Jacqueline I Alvarez-Leite; Elida M Rabelo
Journal:  PLoS Negl Trop Dis       Date:  2014-09-25

8.  Helminth infections and type 2 diabetes: a cluster-randomized placebo controlled SUGARSPIN trial in Nangapanda, Flores, Indonesia.

Authors:  Dicky L Tahapary; Karin de Ruiter; Ivonne Martin; Lisette van Lieshout; Bruno Guigas; Pradana Soewondo; Yenny Djuardi; Aprilianto E Wiria; Oleg A Mayboroda; Jeanine J Houwing-Duistermaat; Hengki Tasman; Erliyani Sartono; Maria Yazdanbakhsh; Johannes W A Smit; Taniawati Supali
Journal:  BMC Infect Dis       Date:  2015-03-18       Impact factor: 3.090

Review 9.  The control of soil-transmitted helminthiases in the Philippines: the story continues.

Authors:  Donald P McManus; Darren J Gray; Mary Lorraine S Mationg; Veronica L Tallo; Gail M Williams; Catherine A Gordon; Archie C A Clements
Journal:  Infect Dis Poverty       Date:  2021-06-12       Impact factor: 10.485

10.  Stunting in pre-school and school-age children in the Peruvian highlands and its association with Fasciola infection and demographic factors.

Authors:  Camille M Webb; Maria Luisa Morales; Martha Lopez; Benicia Baca-Turpo; Eulogia Arque; A Clinton White; Miguel M Cabada
Journal:  PLoS Negl Trop Dis       Date:  2021-06-21
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