Literature DB >> 2470471

Galanin inhibits dopamine secretion and activates a potassium channel in pheochromocytoma cells.

J R de Weille1, M Fosset, H Schmid-Antomarchi, M Lazdunski.   

Abstract

Galanin inhibits depolarization-induced dopamine release from chromaffin cells. In excised membrane patches, galanin induced openings of a 36 pS, inwardly rectifying potassium channel. Galanin activation of this K+ channel was blocked by pretreatment with pertussis toxin. Galanin is without effect on L-type Ca2+ channels.

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Year:  1989        PMID: 2470471     DOI: 10.1016/0006-8993(89)90685-9

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  6 in total

Review 1.  Galanin.

Authors:  M E Vrontakis; A Torsello; H G Friesen
Journal:  J Endocrinol Invest       Date:  1991-10       Impact factor: 4.256

2.  Influence of chronic administration of antidepressant drugs on mRNA for galanin, galanin receptors, and tyrosine hydroxylase in catecholaminergic and serotonergic cell-body regions in rat brain.

Authors:  Molly L Rovin; Katherine A Boss-Williams; Reid S Alisch; James C Ritchie; David Weinshenker; Charles H K West; Jay M Weiss
Journal:  Neuropeptides       Date:  2012-02-10       Impact factor: 3.286

3.  Galanin inhibits a dihydropyridine-sensitive Ca2+ current in the RINm5f cell line.

Authors:  F R Homaidan; G W Sharp; L M Nowak
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-01       Impact factor: 11.205

4.  Galanin receptor 1 gene (Galnr1) is tightly linked to the myelin basic protein gene on chromosome 18 in mouse.

Authors:  D K Simoneaux; R J Leach; P O'Connell
Journal:  Mamm Genome       Date:  1997       Impact factor: 2.957

Review 5.  Regulation of neurological and neuropsychiatric phenotypes by locus coeruleus-derived galanin.

Authors:  David Weinshenker; Philip V Holmes
Journal:  Brain Res       Date:  2015-11-20       Impact factor: 3.252

6.  Galanin inhibits GLP-1 and GIP secretion via the GAL1 receptor in enteroendocrine L and K cells.

Authors:  Arianna Psichas; Leslie L Glass; Stephen J Sharp; Frank Reimann; Fiona M Gribble
Journal:  Br J Pharmacol       Date:  2016-02-08       Impact factor: 8.739

  6 in total

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