| Literature DB >> 24704553 |
Yan-Ping Li1, Yu-Chun Yang2, Yin-Ke Li3, Zhi-Yong Jiang3, Xiang-Zhong Huang3, Wei-Guang Wang4, Xue-Mei Gao5, Qiu-Fen Hu6.
Abstract
Five unusual new prenylated chalcones, renifolins D-H (1-5), were isolated from whole Desmodium renifolium plants. All of their structures were determined by spectroscopic methods including 1D and 2D NMR. All of the isolates were evaluated for cytotoxicity using five tumor cell lines. Compounds 2 and 3 exhibited cytotoxicity against A549 cells, with IC50 values of 2.8 and 2.2 μM, respectively.Entities:
Keywords: 5′-Prenylbutein (PubChem CID: 11267805); Antiarone J (PubChem CID: 42607617); Antiarone K (PubChem CID: 42607618); Cytotoxicity; Desmodium renifolium; Prenylated chalcone
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Year: 2014 PMID： 24704553 DOI： 10.1016/j.fitote.2014.03.026
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882