Ahmet Çağrı Aykan1, Ilker Gül2, Tayyar Gökdeniz2, Engin Hatem2, Ahmet Oğuz Arslan2, Ezgi Kalaycıoğlu2, Turhan Turan2, Erdal Belen3, Mustafa Çetin2. 1. Department of Cardiology, Ahi Evren Chest Cardiovascular Surgery Education and Research Hospital, Trabzon, Turkey. Electronic address: ahmetaykan@yahoo.com. 2. Department of Cardiology, Ahi Evren Chest Cardiovascular Surgery Education and Research Hospital, Trabzon, Turkey. 3. Department of Cardiology, Gaziemir Nevvar Salih İşgören State Hospital, Izmir, Turkey.
Abstract
OBJECTIVES: Epicardial fat thickness (EFT) and Ankle brachial index (ABI) are associated with coronary artery disease (CAD). The SYNTAX score (SS) reflects the complexity of CAD. We aimed to evaluate the relation of EFT and ABI with CAD complexity. METHODS: We enrolled 197 patients undergoing coronary angiography. In all patients, ABI and EFT were determined. SS was calculated. The relationship between EFT, ABI and SS was analysed. RESULTS: ABI and EFT were significantly correlated with SS (r = -0.525, p < 0.001, and r = 0.650, p < 0.001, respectively) and found to be independent predictors of SS. ABI<0.9mm identified patients with SS>22 with a sensitivity of 45.28% and a specificity of %82.64 (AUC = 0.689, %95 CI = 0.619-0.763, p<0.001). The optimal cutoff value for EFT was 5mm, yielding a sensitivity of 81.1% and a specificity of 90.3% (AUC = 0.859, 95% CI 0.802-0.904). In order to identify which parameters were the most accurate, we compared both AUC of ROC curves and there was no difference (p = 0.170). CONCLUSION: EFT and ABI enables the noninvasive prediction of CAD severity in patients with suspected CAD and combining ABI to EFT was additive for the prediction of coronary artery disease complexity.
OBJECTIVES: Epicardial fat thickness (EFT) and Ankle brachial index (ABI) are associated with coronary artery disease (CAD). The SYNTAX score (SS) reflects the complexity of CAD. We aimed to evaluate the relation of EFT and ABI with CAD complexity. METHODS: We enrolled 197 patients undergoing coronary angiography. In all patients, ABI and EFT were determined. SS was calculated. The relationship between EFT, ABI and SS was analysed. RESULTS: ABI and EFT were significantly correlated with SS (r = -0.525, p < 0.001, and r = 0.650, p < 0.001, respectively) and found to be independent predictors of SS. ABI<0.9mm identified patients with SS>22 with a sensitivity of 45.28% and a specificity of %82.64 (AUC = 0.689, %95 CI = 0.619-0.763, p<0.001). The optimal cutoff value for EFT was 5mm, yielding a sensitivity of 81.1% and a specificity of 90.3% (AUC = 0.859, 95% CI 0.802-0.904). In order to identify which parameters were the most accurate, we compared both AUC of ROC curves and there was no difference (p = 0.170). CONCLUSION: EFT and ABI enables the noninvasive prediction of CAD severity in patients with suspected CAD and combining ABI to EFT was additive for the prediction of coronary artery disease complexity.
Authors: Krzysztof L Bryniarski; Tomasz Tokarek; Tomasz Bryk; Joanna Rutka; Iwona Gawlik; Anna Żabówka; Grzegorz Dębski; Beata Bobrowska; Krzysztof Żmudka; Artur Dziewierz; Zbigniew Siudak; Dariusz Dudek Journal: Postepy Kardiol Interwencyjnej Date: 2018-03-22 Impact factor: 1.426