Literature DB >> 24704152

Surgery results in complete cure of Lambert-Eaton myasthenic syndrome in a patient with metastatic Merkel cell carcinoma.

Richard T K Siau1, Andrew Morris2, Richard O S Karoo3.   

Abstract

Lambert-Eaton myasthenic syndrome is a paraneoplastic phenomenon associated with neuroendocrine tumours, most frequently small cell lung carcinoma. Merkel cell carcinoma is a rare cause of Lambert-Eaton myasthenic syndrome. A 70-year old gentleman was referred with metastatic axillary nodal disease from a previously resected Merkel cell carcinoma of the left arm. Pre-operatively, the patient was wheelchair-bound from Lambert-Eaton myasthenic syndrome. Level I-III left axillary node clearance was performed and within 6 months, he had experienced full recovery of muscle power and mobility. We describe a case of complete cure of Lambert-Eaton myasthenic syndrome following axillary nodal clearance in a patient with metastatic Merkel cell carcinoma.
Copyright © 2014 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  LEMS; Lambert–Eaton myasthenic syndrome; Merkel cell carcinoma; Neurology; Paraneoplastic; Surgery

Mesh:

Year:  2014        PMID: 24704152     DOI: 10.1016/j.bjps.2014.03.014

Source DB:  PubMed          Journal:  J Plast Reconstr Aesthet Surg        ISSN: 1748-6815            Impact factor:   2.740


  4 in total

1.  Paraneoplastic syndromes (PNS) associated with Merkel cell carcinoma (MCC): A case series of 8 patients highlighting different clinical manifestations.

Authors:  Jayasri G Iyer; Kaushik Parvathaneni; Shailender Bhatia; Erica S Tarabadkar; Astrid Blom; Ryan Doumani; Jill McKenzie; Maryam M Asgari; Paul Nghiem
Journal:  J Am Acad Dermatol       Date:  2016-05-11       Impact factor: 11.527

Review 2.  Subacute sensory neuronopathy associated with Merkel cell carcinoma with unknown primary: a case report with literature review.

Authors:  Riccardo Milani; Miryam Cannizzaro; Gianluigi Arrigoni; Federica Filipello; Federica Cerri; Massimo Filippi
Journal:  J Neurol       Date:  2022-04-16       Impact factor: 6.682

3.  The European Lambert-Eaton Myasthenic Syndrome Registry: Long-Term Outcomes Following Symptomatic Treatment.

Authors:  Andreas Meisel; Jörn P Sieb; Gwendal Le Masson; Ville Postila; Sabrina Sacconi
Journal:  Neurol Ther       Date:  2022-05-05

4.  Ophthalmoplegia associated with lung adenocarcinoma in a patient with the Lambert-Eaton myasthenic syndrome: A case report.

Authors:  Yufeng Tang; Ke Wang; Zhonglun Chen; Muke Zhou; Jingfeng Duan; Tao Liu; Dong Zhou
Journal:  Medicine (Baltimore)       Date:  2017-06       Impact factor: 1.889

  4 in total

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