Literature DB >> 24703689

Small molecules convert fibroblasts into islet-like cells avoiding pluripotent state.

Nadya Lumelsky1.   

Abstract

Obtaining large numbers of functional pancreatic islets via direct cellular reprogramming is an important clinically relevant goal. In a recent issue of Cell Stem Cell, Li et al. (2014) report a new step-wise protocol for generating islet cells from mouse embryonic fibroblasts using a combination of soluble molecules.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 24703689     DOI: 10.1016/j.cmet.2014.03.019

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  4 in total

Review 1.  Chemical transdifferentiation: closer to regenerative medicine.

Authors:  Aining Xu; Lin Cheng
Journal:  Front Med       Date:  2016-05-03       Impact factor: 4.592

2.  Cell-free culture conditioned medium elicits pancreatic β cell lineage-specific epigenetic reprogramming in mice.

Authors:  Koichi Kawamoto; Tomofumi Ohashi; Masamitsu Konno; Naohiro Nishida; Jun Koseki; Hidetoshi Matsui; Daisuke Sakai; Toshihiro Kudo; Hidetoshi Eguchi; Taroh Satoh; Yuichiro Doki; Masaki Mori; Hideshi Ishii
Journal:  Oncol Lett       Date:  2018-06-21       Impact factor: 2.967

Review 3.  Phenotypic technologies in stem cell biology.

Authors:  J Jeya Vandana; Lauretta A Lacko; Shuibing Chen
Journal:  Cell Chem Biol       Date:  2021-03-01       Impact factor: 8.116

Review 4.  Reprogramming cell fate: a changing story.

Authors:  Michael T Chin
Journal:  Front Cell Dev Biol       Date:  2014-08-27
  4 in total

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