Literature DB >> 24703517

Severity and interference of chronic pain in methadone-maintained outpatients.

Kelly E Dunn1, Robert K Brooner, Michael R Clark.   

Abstract

OBJECTIVES: Patients with opioid use disorder maintained on methadone report more chronic pain than the general population. The current study characterized chronic pain in patients with opioid use disorder.
DESIGN: A one-time self-report survey.
SETTING: The Addiction Treatment Services methadone-maintenance clinic, located on the campus of Johns Hopkins Bayview Medical Center in Baltimore MD.
SUBJECTS: A convenience sample of 227 methadone-maintained patients.
METHODS: Participants completed a one-time self-report administration of the brief pain inventory (BPI) and a demographic survey; additional treatment variables were obtained directly from clinic records.
RESULTS: Sixty percent of the sample endorsed chronic pain. Patients with pain were significantly older, had a higher mean methadone dose, and provided more benzodiazepine-positive urine samples. Pain was primarily located in the lower extremities (59%) and back (51%), and mean BPI severity and interference subscale scores were 5.7 and 5.4 out of 10, respectively. Logistic regressions indicated that age (P < 0.001) and methadone dose (P < 0.001) were significantly associated with having pain and that pain was a significant predictor of benzodiazepine use (P = 0.01). Only 13% (N = 18) of patients with pain were receiving pain management, and few were being treated with any nonopioid adjuvant analgesics. Yet patients who did receive treatment reported a mean 51% improvement in their pain, indicating they are not treatment refractory.
CONCLUSIONS: Results suggest there is a large discrepancy in the percent of patients who may need treatment for pain and those receiving treatment for pain and that more efforts should be made to provide standard pain management techniques to patients with opioid use disorder to reduce their overall level of pain and potentially improve their overall treatment outcomes. Wiley Periodicals, Inc.

Entities:  

Keywords:  Chronic Pain; Methadone; Opioids

Mesh:

Substances:

Year:  2014        PMID: 24703517     DOI: 10.1111/pme.12430

Source DB:  PubMed          Journal:  Pain Med        ISSN: 1526-2375            Impact factor:   3.750


  18 in total

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2.  Characterizing pain and associated coping strategies in methadone and buprenorphine-maintained patients.

Authors:  Kelly E Dunn; Patrick H Finan; D Andrew Tompkins; Michael Fingerhood; Eric C Strain
Journal:  Drug Alcohol Depend       Date:  2015-10-19       Impact factor: 4.492

Review 3.  Caring for patients with opioid use disorder in the hospital.

Authors:  Joseph H Donroe; Stephen R Holt; Jeanette M Tetrault
Journal:  CMAJ       Date:  2016-09-19       Impact factor: 8.262

4.  Pain Among High-Risk Patients on Methadone Maintenance Treatment.

Authors:  Pauline Voon; Kanna Hayashi; M-J Milloy; Paul Nguyen; Evan Wood; Julio Montaner; Thomas Kerr
Journal:  J Pain       Date:  2015-06-21       Impact factor: 5.820

5.  Longitudinal analysis of pain and illicit drug use behaviors in outpatients on methadone maintenance.

Authors:  Lara Dhingra; David C Perlman; Carmen Masson; Jack Chen; Courtney McKnight; Ashly E Jordan; Thomas Wasser; Russell K Portenoy; Martin D Cheatle
Journal:  Drug Alcohol Depend       Date:  2015-02-17       Impact factor: 4.492

6.  Mechanisms and Clinical Features of Co-occurring Opioid and Nicotine Use.

Authors:  Sarah D Lichenstein; Yasmin Zakiniaeiz; Sarah W Yip; Kathleen A Garrison
Journal:  Curr Addict Rep       Date:  2019-04-27

7.  A Retrospective Study of Acute Postoperative Pain After Cesarean Delivery in Patients With Opioid Use Disorder Treated With Opioid Agonist Pharmacotherapy.

Authors:  Johanna Cobb; Wendy Craig; Janelle Richard; Elizabeth Snow; Heather Turcotte; Robert Warters; Aurora Quaye
Journal:  J Addict Med       Date:  2022-02-14       Impact factor: 4.647

8.  Reward Responsiveness in Patients with Opioid Use Disorder on Opioid Agonist Treatment: Role of Comorbid Chronic Pain.

Authors:  Patrick H Finan; Janelle Letzen; David H Epstein; Chung Jung Mun; Samuel Stull; William J Kowalczyk; Daniel Agage; Karran A Phillips; Diego A Pizzagalli; Kenzie L Preston
Journal:  Pain Med       Date:  2021-09-08       Impact factor: 3.750

9.  Associations Among Sleep Disturbance, Pain Catastrophizing, and Pain Intensity for Methadone-maintained Patients With Opioid Use Disorder and Chronic Pain.

Authors:  Caridad Ponce Martinez; Karlyn A Edwards; Corey R Roos; Mark Beitel; Anthony Eller; Declan T Barry
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Review 10.  Impact of Chronic Pain on Treatment Prognosis for Patients with Opioid Use Disorder: A Systematic Review and Meta-analysis.

Authors:  Brittany B Dennis; Monica Bawor; Leen Naji; Carol K Chan; Jaymie Varenbut; James Paul; Michael Varenbut; Jeff Daiter; Carolyn Plater; Guillaume Pare; David C Marsh; Andrew Worster; Dipika Desai; Lehana Thabane; Zainab Samaan
Journal:  Subst Abuse       Date:  2015-09-10
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