| Literature DB >> 24703348 |
Ashika Chhana1, Nicola Dalbeth2.
Abstract
This article summarizes the structural damage that is observed in advanced gout and current understanding of the mechanisms by which this damage occurs. Interactions between monosodium urate crystals and cells within the joint are described as well as knowledge gained from imaging studies. Future research directions and potential therapeutic strategies for the prevention and treatment of joint damage in gout are also discussed.Entities:
Keywords: Bone; Cartilage; Gout; Tendon; Urate crystal
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Year: 2014 PMID： 24703348 DOI： 10.1016/j.rdc.2014.01.006
Source DB: PubMed Journal: Rheum Dis Clin North Am ISSN： 0889-857X Impact factor: 2.670