| Literature DB >> 24703021 |
Fanny Sauvestre1, Dominique Carles2, Martie Faure3, Floriane Taillat3, Fanny Le Boulanger4, Claire Castain5, Gwenaëlle André2, Fanny Pelluard2.
Abstract
Of all the gestational trophoblastic tumors, the gestational choriocarcinomas have the worst prognosis and the most uncommon. We report a case diagnosed on a full-term placenta, discovered incidentally. The patient, gravida 2, para 1, delivered a hypotrophic infant at 38 weeks gestation. The placenta was examined in the laboratory to perform anatomo-pathological examination in order to explain the growth retardation. This study revealed the presence of an intraplacental choriocarcinoma. Disease staging was negative for both mother and child, and beta-HCG levels remained at zero. These two factors are rather good prognosis for choriocarcinoma. With this observation, we highlight the added-value of placental examination, which seems essential for any fetal pathology, pathological pregnancy and intrapartum complications. Anatomo-pathological examination must be meticulous and systematized in order to not overlook an intraplacental tumor.Entities:
Keywords: Choriocarcinome in situ; Choriocarcinome intra-placentaire gestationnel; In situ choriocarcinoma; Intraplacental gestational choriocarcinoma; Placenta; Trophoblastic tumor; Tumeur trophoblastique
Mesh:
Year: 2014 PMID: 24703021 DOI: 10.1016/j.annpat.2014.02.009
Source DB: PubMed Journal: Ann Pathol ISSN: 0242-6498 Impact factor: 0.407