Guo-Lei Zhu1, Qian Hao1, Rong-Tao Li1, Hai-Zhou Li2. 1. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China. 2. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China. Electronic address: lihaizhou@yninfo.com.
Abstract
AIM: To study the chemical constituents of the roots of Asparagus cochinchinensis (Asparagaceae). METHODS: The compounds were isolated with Diaion HP20, silica gel, and ODS chromatography, and their structures were determined on the basis of chemical methods, HR-ESI-MS, and 1D- and 2D-NMR techniques. RESULTS: Seven compounds were isolated from the n-butanol fraction of the roots of A. cochinchinensis, and their structures were elucidated as (25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22α, 26-triol-12-one-3-O-β-D-glucopyranoside (1), (25S)-26-O-β-D-glucopyranosyl-22α-methoxy-5β-furostan-3β, 26-diol-12-one-3-O-β-D-glucopyranoside (2), (25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22α, 26-triol (3), (25S)-26-O-β-D-glucopyranosyl-5β-furstan-3β, 22α, 26-triol-3-O-β-D-glucopyranoside (4), (25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22α, 26-triol-3-O-α-L-rhamnopyranosyl-(1, 4)-β-D-glucopyranoside (5), (25S)-5β-spirostan-3β-ol-3-O-α-L-rhamnopyranoside (6), and (25S)-5β-spirostan-3β-ol-3-O-β-D-glucopyranoside (7). CONCLUSION: Compounds 1 and 2 were two new furostanol saponins.
AIM: To study the chemical constituents of the roots of Asparagus cochinchinensis (Asparagaceae). METHODS: The compounds were isolated with Diaion HP20, silica gel, and ODS chromatography, and their structures were determined on the basis of chemical methods, HR-ESI-MS, and 1D- and 2D-NMR techniques. RESULTS: Seven compounds were isolated from the n-butanol fraction of the roots of A. cochinchinensis, and their structures were elucidated as (25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22α, 26-triol-12-one-3-O-β-D-glucopyranoside (1), (25S)-26-O-β-D-glucopyranosyl-22α-methoxy-5β-furostan-3β, 26-diol-12-one-3-O-β-D-glucopyranoside (2), (25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22α, 26-triol (3), (25S)-26-O-β-D-glucopyranosyl-5β-furstan-3β, 22α, 26-triol-3-O-β-D-glucopyranoside (4), (25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22α, 26-triol-3-O-α-L-rhamnopyranosyl-(1, 4)-β-D-glucopyranoside (5), (25S)-5β-spirostan-3β-ol-3-O-α-L-rhamnopyranoside (6), and (25S)-5β-spirostan-3β-ol-3-O-β-D-glucopyranoside (7). CONCLUSION: Compounds 1 and 2 were two new furostanol saponins.
Authors: Ju Hee Lee; Hun Jai Lim; Chan Woo Lee; Kun-Ho Son; Jong-Keun Son; Sang Kook Lee; Hyun Pyo Kim Journal: Evid Based Complement Alternat Med Date: 2015-08-25 Impact factor: 2.629
Authors: Hyun Ah Lee; Bo Ram Song; Hye Ryeong Kim; Ji Eun Kim; Woo Bin Yun; Jin Ju Park; Mi Lim Lee; Jun Young Choi; Hee Seob Lee; Dae Youn Hwang Journal: Exp Ther Med Date: 2017-09-25 Impact factor: 2.447