Literature DB >> 24702102

Fifteen-year trends and predictors of preparation for pregnancy in women with pre-conception Type 1 and Type 2 diabetes: a population-based cohort study.

S V Glinianaia1, P W G Tennant, D Crowder, R Nayar, R Bell.   

Abstract

AIMS: To investigate trends in indicators of preparation for pregnancy in women with Type 1 and Type 2 diabetes and explore their predictors.
METHODS: Data on 2293 pregnancies delivered during 1996-2010 by women with Type 1 (n = 1753) and Type 2 (n = 540) diabetes were obtained from the Northern Diabetes in Pregnancy Survey. Multiple logistic regression was used to analyse the relationship between potential predictors and three indicators of inadequate pregnancy preparation: non-attendance for pre-conception care; no pre-conception folate consumption; and peri-conception HbA(1c) ≥ 53 mmol/mol (≥ 7%).
RESULTS: Overall, 40.3% of women with diabetes attended pre-conception care, 37.4% reported pre-conception folate consumption, and 28.2% had adequate peri-conception HbA1c . For all patients, pre-conception folate consumption improved over time, while peri-conception glucose control did not. Attendance for pre-conception care for women with Type 1 diabetes significantly declined. Residence in deprived areas, smoking and younger maternal age (for women aged < 35 years) were independently associated with all three indicators of inadequate preparation for pregnancy. Additional predictors of inadequate peri-conception HbA(1c) were: Type 1 diabetes (adjusted odds ratio 5.51, 95% CI 2.71-11.22), longer diabetes history (adjusted odds ratio 1.16, 95% CI 1.09-1.23 per year increase for those with < 15 years' diabetes duration), non-white ethnicity (adjusted odds ratio 3.13, 95% CI 1.23-7.97) and higher BMI (adjusted odds ratio 1.05, 95% CI 1.01-1.09 per 1-kg/m(2) increase). Non-attendance for pre-conception care was additionally associated with Type 2 diabetes (P = 0.003) and multiparity (P < 0.0001).
CONCLUSIONS: There are socio-demographic inequalities in preparation for pregnancy among women with diabetes. Women with Type 2 diabetes were less likely to attend pre-conception care. Pre-conception services need to be designed to maximize uptake in all groups.
© 2014 The Authors. Diabetic Medicine © 2014 Diabetes UK.

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Year:  2014        PMID: 24702102     DOI: 10.1111/dme.12460

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  5 in total

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2.  A core outcome set for studies evaluating the effectiveness of prepregnancy care for women with pregestational diabetes.

Authors:  Aoife M Egan; Sander Galjaard; Michael J A Maresh; Mary R Loeken; Angela Napoli; Eleni Anastasiou; Eoin Noctor; Harold W de Valk; Mireille van Poppel; Marie Todd; Valerie Smith; Declan Devane; Fidelma P Dunne
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3.  Risk estimates of recurrent congenital anomalies in the UK: a population-based register study.

Authors:  Svetlana V Glinianaia; Peter W G Tennant; Judith Rankin
Journal:  BMC Med       Date:  2017-01-31       Impact factor: 8.775

4.  Factors influencing pregnancy planning of multi-ethnic Asian women with diabetes: A qualitative study.

Authors:  Irmi Z I; Ng C J; Lee P Y; Hussein N
Journal:  PLoS One       Date:  2020-12-03       Impact factor: 3.240

5.  Preconception care in Saudi women with diabetes mellitus.

Authors:  Amal Y Madanat; Eman A Sheshah
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  5 in total

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