Literature DB >> 24701530

Synchronous Multicentric Giant Cell Tumour (GCT)-A Rare Case Report.

Anshu Shekhar1, Gururaj Murgod2, Suresh Korlhalli3.   

Abstract

Giant Cell Tumours (GCT) of bone account for 5% of all primary bone tumours. Multicentric variety is a rare variant of this condition, accounting for less than 1% of all cases and can occur as synchronous or metachronous lesions. We report a 22-year-old male patient with 18 months history of painful progressive swellings around the right knee. Radiographs revealed expansile lytic lesions in the distal femur, proximal tibia and fibula and core needle biopsy was typical of GCT. Biochemical parameters were normal and radiological investigations did not reveal any metastasis. The patient was treated by above knee amputation due to the extensive nature of the tumours. The excised tissue from all sites had features of giant cell tumor with no atypia or malignant cells seen. The patient is free from recurrence or metastasis at three years follow up.

Entities:  

Keywords:  Amputation; Neoplasms; Synchronous multiple primary

Year:  2014        PMID: 24701530      PMCID: PMC3972558          DOI: 10.7860/JCDR/2014/8153.4055

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  8 in total

1.  Giant-cell tumor of bone: an historical perspective.

Authors:  E F McCarthy
Journal:  Clin Orthop Relat Res       Date:  1980 Nov-Dec       Impact factor: 4.176

2.  Multicentric giant cell tumor of bone. Clinicopathologic analysis of thirty cases.

Authors:  Benjamin Hoch; Carrie Inwards; Murali Sundaram; Andrew E Rosenberg
Journal:  J Bone Joint Surg Am       Date:  2006-09       Impact factor: 5.284

Review 3.  Multicentric giant cell tumour of bone.

Authors:  Mandeep S Dhillon; Prabhudev Prasad
Journal:  Acta Orthop Belg       Date:  2007-06       Impact factor: 0.500

4.  Multicentric giant-cell tumor of bone.

Authors:  F H Sim; D C Dahlin; J W Beabout
Journal:  J Bone Joint Surg Am       Date:  1977-12       Impact factor: 5.284

5.  Treatment of giant cell tumor of bone: Current concepts.

Authors:  Ajay Puri; Manish Agarwal
Journal:  Indian J Orthop       Date:  2007-04       Impact factor: 1.251

6.  Multicentric giant cell tumor of bone: ten lesions at presentation.

Authors:  Il-Hyung Park; In-Ho Jeon
Journal:  Skeletal Radiol       Date:  2003-07-22       Impact factor: 2.199

7.  Giant-cell tumor of bone.

Authors:  M Campanacci; N Baldini; S Boriani; A Sudanese
Journal:  J Bone Joint Surg Am       Date:  1987-01       Impact factor: 5.284

8.  Multicentric giant cell tumor of bone: synchronous and metachronous presentation.

Authors:  Reiner Wirbel; Frank Blümler; Dirk Lommel; Guido Syré; Veit Krenn
Journal:  Case Rep Orthop       Date:  2013-09-11
  8 in total
  1 in total

1.  Metachronous multicentric giant cell tumour of bone.

Authors:  Navatha Vangala; Shantveer G Uppin; Sobiya Mehnaz Ayesha; K R Harshavardhana; P Chandrasekhar
Journal:  Skeletal Radiol       Date:  2018-05-03       Impact factor: 2.199

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.