Literature DB >> 24700960

Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome.

Pravin U Shingade1, Vaishali Wankhede2, Pritam S Kataria1, Nitin Sonone1.   

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare drug induced cutaneous hypersensitivity reaction characterized by sudden onset of fever with sterile pustules overlying an erythematous skin occurring all over the body. The offending drugs are usually B-lactams and macrolides. Among anticonvulsants carbamazepine and Phenobarbital are commonly associated with AGEP. Only one case of phenytoin induced AGEP has been reported in literature. We present a rare case of AGEP with cerebellar syndrome occurring after receiving loading dose of phenytoin.

Entities:  

Keywords:  Acute generalized exanthematous pustulosis; cerebellar syndrome; phenytoin

Year:  2014        PMID: 24700960      PMCID: PMC3969702          DOI: 10.4103/0019-5154.127715

Source DB:  PubMed          Journal:  Indian J Dermatol        ISSN: 0019-5154            Impact factor:   1.494


  8 in total

Review 1.  Acute generalized exanthematous pustulosis (AGEP)--a clinical reaction pattern.

Authors:  A Sidoroff; S Halevy; J N Bavinck; L Vaillant; J C Roujeau
Journal:  J Cutan Pathol       Date:  2001-03       Impact factor: 1.587

2.  Phenytoin-induced acute generalized exanthemous pustulosis.

Authors:  Nasir Aziz; Samantha Toerge; Thomas Nigra
Journal:  J Am Acad Dermatol       Date:  2010-04       Impact factor: 11.527

Review 3.  Acute generalized exanthematous pustulosis: an overview of the clinical, immunological and diagnostic concepts.

Authors:  Marijn M Speeckaert; Reinhart Speeckaert; Jo Lambert; Lieve Brochez
Journal:  Eur J Dermatol       Date:  2010-06-14       Impact factor: 3.328

4.  [Acute generalized exanthematic pustuloses (four cases) (author's transl)].

Authors:  C Beylot; P Bioulac; M S Doutre
Journal:  Ann Dermatol Venereol       Date:  1980 Jan-Feb       Impact factor: 0.777

Review 5.  Acute generalized exanthematous pustulosis: report of 12 cases and literature review.

Authors:  Elizabeth Guevara-Gutierrez; Elia Uribe-Jimenez; Margarita Diaz-Canchola; Alberto Tlacuilo-Parra
Journal:  Int J Dermatol       Date:  2009-03       Impact factor: 2.736

6.  Acute generalized exanthematous pustulosis. Analysis of 63 cases.

Authors:  J C Roujeau; P Bioulac-Sage; C Bourseau; J C Guillaume; P Bernard; C Lok; P Plantin; A Claudy; C Delavierre; L Vaillant
Journal:  Arch Dermatol       Date:  1991-09

7.  Hydroxyzine-induced acute generalized exanthematous pustulosis: an uncommon side effect of a common drug.

Authors:  Sorna L Kumar; Reena Rai
Journal:  Indian J Dermatol       Date:  2011-07       Impact factor: 1.494

8.  Drug Eruptions: An 8-year Study Including 106 Inpatients at a Dermatology Clinic in Turkey.

Authors:  Fatma Akpinar; Emine Dervis
Journal:  Indian J Dermatol       Date:  2012-05       Impact factor: 1.494

  8 in total
  2 in total

Review 1.  Acute Generalized Exanthematous Pustulosis: Pathogenesis, Genetic Background, Clinical Variants and Therapy.

Authors:  Laurence Feldmeyer; Kristine Heidemeyer; Nikhil Yawalkar
Journal:  Int J Mol Sci       Date:  2016-07-27       Impact factor: 5.923

Review 2.  Drug Triggers and Clinic of Acute Generalized Exanthematous Pustulosis (AGEP): A Literature Case Series of 297 Patients.

Authors:  Enriqueta Vallejo-Yagüe; Adrian Martinez-De la Torre; Omar S Mohamad; Shweta Sabu; Andrea M Burden
Journal:  J Clin Med       Date:  2022-01-13       Impact factor: 4.241

  2 in total

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