| Literature DB >> 24699896 |
Zhen Wang1, Qian Yao, Tengfei Kang, Juhua Feng, Xiaohua Liu, Lili Lin, Xiaoming Feng.
Abstract
An efficient lanthanide(III)-catalyzed diastereo- and enantioselective Michael addition of 3-substituted benzofuran-2(3H)-ones to 4-oxo-enoates was developed. The desired adducts with contiguous quaternary-tertiary stereocenters were obtained in up to 99% yield with up to >95/5 dr and 98% ee.Entities:
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Year: 2014 PMID： 24699896 DOI： 10.1039/c4cc01499e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222