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Literature DB >> 24698433

Overcoming the current deadlock in antibiotic research.

Abstract

Antibiotic-resistant bacteria are on the rise, making it harder to treat bacterial infections. The situation is aggravated by the shrinking of the antibiotic development pipeline. To finance urgently needed incentives for antibiotic research, creative financing solutions are needed. Public-private partnerships (PPPs) are a successful model for moving forward.

Entities: Disease

Keywords: antibiotic resistance; public health; public–private partnership (PPP)

Mesh：

Substances：
Anti-Bacterial Agents

Year: 2014 PMID： 24698433 DOI： 10.1016/j.tim.2013.12.007

Source DB: PubMed Journal: Trends Microbiol ISSN： 0966-842X Impact factor: 17.079

Keyword Cloud
Cited

34 in total

1. Nanomedicine in the Management of Microbial Infection - Overview and Perspectives.

Authors: Xi Zhu; Aleksandar F Radovic-Moreno; Jun Wu; Robert Langer; Jinjun Shi
Journal: Nano Today Date: 2014-08-01 Impact factor: 20.722

2. Intracellular localization of polymyxins in human alveolar epithelial cells.

Authors: Maizbha U Ahmed; Tony Velkov; Qi Tony Zhou; Alex J Fulcher; Judy Callaghan; Fanfan Zhou; Kim Chan; Mohammad A K Azad; Jian Li
Journal: J Antimicrob Chemother Date: 2019-01-01 Impact factor: 5.790

3. Docking and molecular dynamics studies on triclosan derivatives binding to FabI.

Authors: Xuyun Yang; Junrui Lu; Ming Ying; Jiangbei Mu; Peichun Li; Yue Liu
Journal: J Mol Model Date: 2017-01-07 Impact factor: 1.810

Review 4. Virulence Factor Targeting of the Bacterial Pathogen Staphylococcus aureus for Vaccine and Therapeutics.

Authors: Trevor L Kane; Katelyn E Carothers; Shaun W Lee
Journal: Curr Drug Targets Date: 2018 Impact factor: 3.465

5. Experimental Evolution of Diverse Strains as a Method for the Determination of Biochemical Mechanisms of Action for Novel Pyrrolizidinone Antibiotics.

Authors: Kathryn Beabout; Megan D McCurry; Heer Mehta; Akshay A Shah; Kiran Kumar Pulukuri; Stephan Rigol; Yanping Wang; K C Nicolaou; Yousif Shamoo
Journal: ACS Infect Dis Date: 2017-09-27 Impact factor: 5.084

Review 10. Harnessing bacterial interactions to manage infections: a review on the opportunistic pathogen Pseudomonas aeruginosa as a case example.

Authors: Chiara Rezzoagli; Elisa T Granato; Rolf Kümmerli
Journal: J Med Microbiol Date: 2020-01-21 Impact factor: 2.472

Overcoming the current deadlock in antibiotic research.

1. Nanomedicine in the Management of Microbial Infection - Overview and Perspectives.

2. Intracellular localization of polymyxins in human alveolar epithelial cells.

3. Docking and molecular dynamics studies on triclosan derivatives binding to FabI.

Review 4. Virulence Factor Targeting of the Bacterial Pathogen Staphylococcus aureus for Vaccine and Therapeutics.

5. Experimental Evolution of Diverse Strains as a Method for the Determination of Biochemical Mechanisms of Action for Novel Pyrrolizidinone Antibiotics.

6. Repurposing salicylamide for combating multidrug-resistant Neisseria gonorrhoeae.

7. The bacterial type III secretion system as a target for developing new antibiotics.

8. Dual Targeting of Cell Wall Precursors by Teixobactin Leads to Cell Lysis.

Review 9. Steering Phages to Combat Bacterial Pathogens.

Review 10. Harnessing bacterial interactions to manage infections: a review on the opportunistic pathogen Pseudomonas aeruginosa as a case example.