| Literature DB >> 2469771 |
T Noma1, H Nakakubo, M Sugita, S Kumagai, M Maeda, A Shimizu, T Honjo.
Abstract
We have analyzed expression patterns of 7 lymphokine mRNAs by Northern blot analyses in 19 different human T cell clones derived from patients with adult T cell leukemia. However, we were not able to reveal particular combinations of lymphokine production that allowed classification of human T cells. Especially, four clonally related leukemic lines that were established independently from the same patient with adult T cell leukemia expressed different combinations of lymphokine mRNAs, indicating that the expression of various lymphokines is not fixed but rather variable even among progenies of a single T cell clone.Entities:
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Year: 1989 PMID: 2469771 PMCID: PMC2189311 DOI: 10.1084/jem.169.5.1853
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307