Literature DB >> 2469145

Interferons in cell growth and development.

G Romeo, G Fiorucci, G B Rossi.   

Abstract

Interferons (IFNs), besides inducing an antiviral state in uninfected cells, are also natural regulatory molecules. They play a key role in the regulation both of cell growth and differentiation, and of development. Up- or down-regulation of oncogenes by IFNs may be one of the mechanisms by which these molecules affect cell physiology. The list of IFN-inducible proteins continues to grow rapidly and future research should identify among these the mediators of the biological effects of IFNs.

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Year:  1989        PMID： 2469145     DOI： 10.1016/0168-9525(89)90007-3

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  8 in total

1.  High-affinity binding of interferon-gamma to a basement membrane complex (matrigel).

Authors:  H Lortat-Jacob; H K Kleinman; J A Grimaud
Journal:  J Clin Invest       Date:  1991-03       Impact factor: 14.808

2.  A phase 2 study of pegylated interferon α-2b (PEG-Intron(®)) in children with diffuse intrinsic pontine glioma.

Authors:  Katherine Warren; Robyn Bent; Pamela L Wolters; Alisa Prager; Ryan Hanson; Roger Packer; Joanna Shih; Kevin Camphausen
Journal:  Cancer       Date:  2011-11-15       Impact factor: 6.860

3.  Human cytomegalovirus UL69 protein induces cells to accumulate in G1 phase of the cell cycle.

Authors:  M Lu; T Shenk
Journal:  J Virol       Date:  1999-01       Impact factor: 5.103

4.  Gamma-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo.

Authors:  V W Yong; R Moumdjian; F P Yong; T C Ruijs; M S Freedman; N Cashman; J P Antel
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-15       Impact factor: 11.205

5.  Deletions at the C-terminus of interferon gamma reduce RNA binding and activation of double-stranded-RNA cleavage by bovine seminal ribonuclease.

Authors:  C H Schein; M Haugg
Journal:  Biochem J       Date:  1995-04-01       Impact factor: 3.857

6.  A factor induced by differentiation signals in cells of the macrophage lineage binds to the gamma interferon activation site.

Authors:  A Eilers; M Baccarini; F Horn; R A Hipskind; C Schindler; T Decker
Journal:  Mol Cell Biol       Date:  1994-02       Impact factor: 4.272

7.  Action of spontaneously produced beta interferon in differentiation of embryonal carcinoma cells through an autoinduction mechanism.

Authors:  P Belhumeur; J Lanoix; Y Blais; D Forget; A Steyaert; D Skup
Journal:  Mol Cell Biol       Date:  1993-05       Impact factor: 4.272

8.  Repression of beta interferon gene expression in virus-infected cells is correlated with a poly(A) tail elongation.

Authors:  E Dehlin; A von Gabain; G Alm; R Dingelmaier; O Resnekov
Journal:  Mol Cell Biol       Date:  1996-02       Impact factor: 4.272
  8 in total

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