Literature DB >> 24691256

Understanding tissue context influences on intratumour heterogeneity.

Franziska Michor1, Valerie M Weaver2.   

Abstract

Although human cancers exhibit intratumour heterogeneity, the influence of the tumour environment on this property is unclear. Single basal-like mammary epithelial cells are now shown to engage a dynamic TGFBR3-JUND signalling circuit in an extracellular-matrix-dependent manner. Cell transition between the distinct gene expression states underlying this circuit alters their properties and may modulate their propensity to malignancy.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24691256      PMCID： PMC4180082          DOI： 10.1038/ncb2942

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  13 in total

1.  Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.

Authors:  Matt van de Rijn; Charles M Perou; Rob Tibshirani; Phillippe Haas; Olli Kallioniemi; Juha Kononen; Joachim Torhorst; Guido Sauter; Markus Zuber; Ossi R Köchli; Frank Mross; Holger Dieterich; Rob Seitz; Doug Ross; David Botstein; Pat Brown
Journal:  Am J Pathol       Date:  2002-12       Impact factor: 4.307

Review 2.  Tumor-host interactions: a far-reaching relationship.

Authors:  Sandra S McAllister; Robert A Weinberg
Journal:  J Clin Oncol       Date:  2010-07-19       Impact factor: 44.544

3.  Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs.

Authors:  Thordur Oskarsson; Swarnali Acharyya; Xiang H-F Zhang; Sakari Vanharanta; Sohail F Tavazoie; Patrick G Morris; Robert J Downey; Katia Manova-Todorova; Edi Brogi; Joan Massagué
Journal:  Nat Med       Date:  2011-06-26       Impact factor: 53.440

4.  Genetic clonal diversity predicts progression to esophageal adenocarcinoma.

Authors:  Carlo C Maley; Patricia C Galipeau; Jennifer C Finley; V Jon Wongsurawat; Xiaohong Li; Carissa A Sanchez; Thomas G Paulson; Patricia L Blount; Rosa-Ana Risques; Peter S Rabinovitch; Brian J Reid
Journal:  Nat Genet       Date:  2006-03-26       Impact factor: 38.330

5.  Intratumor heterogeneity: seeing the wood for the trees.

Authors:  Timothy A Yap; Marco Gerlinger; P Andrew Futreal; Lajos Pusztai; Charles Swanton
Journal:  Sci Transl Med       Date:  2012-03-28       Impact factor: 17.956

Review 6.  Putting tumours in context.

Authors:  M J Bissell; D Radisky
Journal:  Nat Rev Cancer       Date:  2001-10       Impact factor: 60.716

Review 7.  Clonal evolution in cancer.

Authors:  Mel Greaves; Carlo C Maley
Journal:  Nature       Date:  2012-01-18       Impact factor: 49.962

8.  Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity.

Authors:  Vanessa Almendro; Yu-Kang Cheng; Amanda Randles; Shalev Itzkovitz; Andriy Marusyk; Elisabet Ametller; Xavier Gonzalez-Farre; Montse Muñoz; Hege G Russnes; Aslaug Helland; Inga H Rye; Anne-Lise Borresen-Dale; Reo Maruyama; Alexander van Oudenaarden; Mitchell Dowsett; Robin L Jones; Jorge Reis-Filho; Pere Gascon; Mithat Gönen; Franziska Michor; Kornelia Polyak
Journal:  Cell Rep       Date:  2014-01-23       Impact factor: 9.423

Review 9.  Stromal fibroblasts in cancer initiation and progression.

Authors:  Neil A Bhowmick; Eric G Neilson; Harold L Moses
Journal:  Nature       Date:  2004-11-18       Impact factor: 49.962

10.  A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies.

Authors:  Chun-Chao Wang; Sameer S Bajikar; Leen Jamal; Kristen A Atkins; Kevin A Janes
Journal:  Nat Cell Biol       Date:  2014-03-23       Impact factor: 28.824
View more
  12 in total

1.  Micropharmacology: An In Silico Approach for Assessing Drug Efficacy Within a Tumor Tissue.

Authors:  Aleksandra Karolak; Katarzyna A Rejniak
Journal:  Bull Math Biol       Date:  2018-02-08       Impact factor: 1.758

2.  Anticancer and chemosensitization effects of cannabidiol in 2D and 3D cultures of TNBC: involvement of GADD45α, integrin-α5, -β5, -β1, and autophagy.

Authors:  Sunil Kumar Surapaneni; Nilkumar Patel; Li Sun; Nagavendra Kommineni; Anil Kumar Kalvala; Aragaw Gebeyehu; Peggy Arthur; Leanne C Duke; Ramesh Nimma; David G Meckes; Mandip Singh
Journal:  Drug Deliv Transl Res       Date:  2022-02-25       Impact factor: 5.671

Review 3.  Maintaining Tumor Heterogeneity in Patient-Derived Tumor Xenografts.

Authors:  John W Cassidy; Carlos Caldas; Alejandra Bruna
Journal:  Cancer Res       Date:  2015-07-15       Impact factor: 12.701

Review 4.  Evolving concepts of tumor heterogeneity.

Authors:  Victoria R Zellmer; Siyuan Zhang
Journal:  Cell Biosci       Date:  2014-11-25       Impact factor: 7.133

5.  Spontaneously-forming spheroids as an in vitro cancer cell model for anticancer drug screening.

Authors:  Maria A Theodoraki; Celso O Rezende; Oraphin Chantarasriwong; Adriana D Corben; Emmanuel A Theodorakis; Mary L Alpaugh
Journal:  Oncotarget       Date:  2015-08-28

6.  Human colorectal cancer progression correlates with LOX-induced ECM stiffening.

Authors:  Bo Wei; Xueling Zhou; Chenghua Liang; Xiaoming Zheng; Purun Lei; Jiafeng Fang; Xiaoyan Han; Lijing Wang; Cuiling Qi; Hongbo Wei
Journal:  Int J Biol Sci       Date:  2017-11-01       Impact factor: 6.580

7.  Cancer stem cells and early stage basal-like breast cancer.

Authors:  Pang-Kuo Lo; Benjamin Wolfson; Qun Zhou
Journal:  World J Obstet Gynecol       Date:  2016-05-10

Review 8.  From Chemotherapy to Combined Targeted Therapeutics: In Vitro and in Vivo Models to Decipher Intra-tumor Heterogeneity.

Authors:  Guido Gambara; Manuela Gaebler; Ulrich Keilholz; Christian R A Regenbrecht; Alessandra Silvestri
Journal:  Front Pharmacol       Date:  2018-02-14       Impact factor: 5.810

9.  The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface.

Authors:  Li Hui Tan; Peter H Sykes; Maan M Alkaisi; John J Evans
Journal:  Int J Nanomedicine       Date:  2015-08-03

10.  Biliary tract cancer patient-derived xenografts: Surgeon impact on individualized medicine.

Authors:  Jennifer L Leiting; Stephen J Murphy; John R Bergquist; Matthew C Hernandez; Tommy Ivanics; Amro M Abdelrahman; Lin Yang; Isaac Lynch; James B Smadbeck; Sean P Cleary; David M Nagorney; Michael S Torbenson; Rondell P Graham; Lewis R Roberts; Gregory J Gores; Rory L Smoot; Mark J Truty
Journal:  JHEP Rep       Date:  2020-01-16
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.