Literature DB >> 24691192

[Cancer-associated venous thromboembolic recurrence: disregard of treatment recommendations].

Isabelle Mahé1, Jean Chidiac1.   

Abstract

Low-molecular-weight heparins (LMWH) are the reference curative treatment of venous thromboembolism (VTE) in patients with cancer. All international guidelines recommend the long-term use of LMWH given their demonstrated superiority compared to vitamin-K antagonists (VKA) in reducing VTE recurrence in this patient population without increased risk of bleeding. However, several studies consistently show a lack of adherence to treatment recommendations, which are applied at the very best in 50% of cases. This results in a loss of chance for patients with fragile prognosis and in whom VTE represents the second cause of death. Given the expected benefit and the increased VTE prevalence in patients with cancer, full awareness is necessary to implement programs aiming at improving the therapeutic management of cancer-associated VTE. This requires multidisciplinary consideration by qualified physicians involved in the management of patients with cancer-associated VTE such as oncologists, internists and those specialized in vascular disease and hemostasis.

Entities:  

Keywords:  anticoagulants; cancer; low-molecular-weight heparin; treatment guidelines; venous thromboembolism

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Year:  2014        PMID: 24691192     DOI: 10.1684/bdc.2014.1907

Source DB:  PubMed          Journal:  Bull Cancer        ISSN: 0007-4551            Impact factor:   1.276


  2 in total

1.  Impact of a dedicated cancer-associated thrombosis service on clinical outcomes: a mixed-methods evaluation of a clinical improvement exercise.

Authors:  Simon Noble; Nikki Pease; Jessica Sui; James Davies; Sarah Lewis; Usman Malik; Raza Alikhan; Hayley Prout; Annmarie Nelson
Journal:  BMJ Open       Date:  2016-11-28       Impact factor: 2.692

2.  Assessing patients' anticoagulation preferences for the treatment of cancer-associated thrombosis using conjoint methodology.

Authors:  Simon Noble; Axel Matzdorff; Anthony Maraveyas; Majbrit V Holm; Giovanni Pisa
Journal:  Haematologica       Date:  2015-08-20       Impact factor: 9.941

  2 in total

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