Literature DB >> 24690977

A case of tick-bite-induced red meat allergy.

Marc F Wuerdeman1, Joshua M Harrison1.   

Abstract

Delayed hypersensitivity disorders and food allergies are often challenging for the clinician and patient alike. A recent discovery of an IgE antibody specific to galactose-α-1,3-galactose, which is a carbohydrate abundantly expressed on cells and tissues of beef, pork, and lamb, adds one more tool to aid the clinician in making the appropriate diagnosis. A link has been discovered between the bite of the Lone Star Tick (Amblyomma americanum) and the development of sensitivity to galactose-α-1,3-galactose. With a high prevalence of Lone Star Tick populations inhabiting major U.S. Army Installations, and the type of duty required by our Service members, it could potentially affect susceptible individuals. We describe a case of an active duty soldier who went 4 years searching for this elusive diagnosis and connection and discuss why it should remain in the differential diagnosis when treating military health care beneficiaries. Reprint &
Copyright © 2014 Association of Military Surgeons of the U.S.

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Year:  2014        PMID: 24690977     DOI: 10.7205/MILMED-D-13-00369

Source DB:  PubMed          Journal:  Mil Med        ISSN: 0026-4075            Impact factor:   1.437


  4 in total

1.  Discovery of Alpha-Gal-Containing Antigens in North American Tick Species Believed to Induce Red Meat Allergy.

Authors:  Gary Crispell; Scott P Commins; Stephanie A Archer-Hartman; Shailesh Choudhary; Guha Dharmarajan; Parastoo Azadi; Shahid Karim
Journal:  Front Immunol       Date:  2019-05-17       Impact factor: 7.561

2.  The predominance of seafood allergy in Vietnamese adults: Results from the first population-based questionnaire survey.

Authors:  Thu T K Le; Thuy T B Tran; Huong T M Ho; An T L Vu; Emma McBryde; Andreas L Lopata
Journal:  World Allergy Organ J       Date:  2020-03-05       Impact factor: 4.084

3.  Alpha-Gal Syndrome: Involvement of Amblyomma americanum α-D-Galactosidase and β-1,4 Galactosyltransferase Enzymes in α-Gal Metabolism.

Authors:  Surendra Raj Sharma; Gary Crispell; Ahmed Mohamed; Cameron Cox; Joshua Lange; Shailesh Choudhary; Scott P Commins; Shahid Karim
Journal:  Front Cell Infect Microbiol       Date:  2021-12-01       Impact factor: 6.073

Review 4.  Current and Future Strategies for the Diagnosis and Treatment of the Alpha-Gal Syndrome (AGS).

Authors:  Rita Vaz-Rodrigues; Lorena Mazuecos; José de la Fuente
Journal:  J Asthma Allergy       Date:  2022-07-18
  4 in total

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