Literature DB >> 24687932

Sustained autoimmune mechanisms in dermatomyositis.

Steven A Greenberg1.   

Abstract

Dermatomyositis is an autoimmune disease predominantly affecting skin and muscle. Its poorly understood pathogenesis is increasingly being linked to the overproduction of type 1 interferon-inducible gene transcripts and proteins. Mechanisms have been identified by which chronic sustained accumulation of these proteins might occur and thereby injure tissue in dermatomyositis.
Copyright © 2014 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

Entities:  

Keywords:  dermatomyositis; innate immune system; type 1 interferon

Mesh:

Substances:

Year:  2014        PMID: 24687932     DOI: 10.1002/path.4355

Source DB:  PubMed          Journal:  J Pathol        ISSN: 0022-3417            Impact factor:   7.996


  6 in total

Review 1.  Juvenile dermatomyositis resembling late-stage Degos disease with gastrointestinal perforations successfully treated with combination of cyclophosphamide and rituximab: case-based review.

Authors:  William Day; Christos Gabriel; Robert E Kelly; Cynthia M Magro; Judith V Williams; Alice Werner; Laura Gifford; Sameer P Lapsia; Cassyanne L Aguiar
Journal:  Rheumatol Int       Date:  2020-01-03       Impact factor: 2.631

2.  Systemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology.

Authors:  Elise Siegert; Akinori Uruha; Carsten Dittmayer; Werner Stenzel; Hans-Hilmar Goebel; Corinna Preuße; Vincent Casteleyn; Felix Kleefeld; Rieke Alten; Gerd R Burmester; Udo Schneider; Jakob Höppner; Kathrin Hahn
Journal:  Acta Neuropathol       Date:  2021-04-17       Impact factor: 17.088

3.  RIG-I expression in perifascicular myofibers is a reliable biomarker of dermatomyositis.

Authors:  Xavier Suárez-Calvet; Eduard Gallardo; Iago Pinal-Fernandez; Noemi De Luna; Cinta Lleixà; Jordi Díaz-Manera; Ricardo Rojas-García; Ivan Castellví; M Angeles Martínez; Josep M Grau; Albert Selva-O'Callaghan; Isabel Illa
Journal:  Arthritis Res Ther       Date:  2017-07-24       Impact factor: 5.156

4.  The RIG-I pathway is involved in peripheral T cell lymphopenia in patients with dermatomyositis.

Authors:  Lu Zhang; Qisheng Xia; Wenli Li; Qinglin Peng; Hanbo Yang; Xin Lu; Guochun Wang
Journal:  Arthritis Res Ther       Date:  2019-05-29       Impact factor: 5.156

5.  Lagophthalmos as a presenting sign in dermatomyositis with muscle involvement limited to the ocular muscles.

Authors:  Jordanna Roesler; Donald Jenkins
Journal:  JAAD Case Rep       Date:  2021-02-10

6.  Differential roles of hypoxia and innate immunity in juvenile and adult dermatomyositis.

Authors:  Corinna Preuße; Yves Allenbach; Olaf Hoffmann; Hans-Hilmar Goebel; Debora Pehl; Josefine Radke; Alexandra Doeser; Udo Schneider; Rieke H E Alten; Tilmann Kallinich; Olivier Benveniste; Arpad von Moers; Benedikt Schoser; Ulrike Schara; Werner Stenzel
Journal:  Acta Neuropathol Commun       Date:  2016-04-27       Impact factor: 7.801

  6 in total

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