Literature DB >> 24687610

Drug handling in a paediatric intensive care unit--can errors be prevented by a three-step intervention?

D Niemann1, A Bertsche2, D Meyrath3, S Oelsner3, A L Ewen3, B Pickardt3, T Henhapl4, G Hoffmann4, J Meyburg4, T Bertsche1.   

Abstract

BACKGROUND: Drug handling in paediatric intensive care units (PICU) is prone to medication errors. We aimed to identify type and prevalence of those errors and to assess preventative interventions.
METHODS: Prospective intervention study investigating a 3-step intervention for preventing errors in drug handling in a 10-bed PICU of a university hospital. Nurses' drug handling was monitored in daily routine to identify the number of patients affected by errors and overall prevalence and types of errors in drug handling. We implemented a comprehensive intervention consisting of an information handout, a training course, and a 76-page reference book tailored to reduce the prevalence.
RESULTS: The prevalence of errors in drug handling decreased from 83 % (555 errors/668 processes)to 63 % (554/883; p < 0.001) after the intervention. The number of affected patients remained unchanged (95 % vs. 89 %, p = 0.370).Peroral (PO) drugs (1.33 errors/process) were more error-prone than intravenous (IV) drugs(0.64), despite being used less frequently (27 % vs.73 % of all processes, p < 0.001). The interventions decreased the prevalence to 0.77 errors/process(p < 0.001) in PO and to 0.52 in IV drugs (p = 0.025).
CONCLUSION: Errors in drug handling were alarmingly frequent. PO drugs were frequently subject to errors, even though being used less frequently. The implementation of a comprehensive intervention succeeded in reducing the prevalence of errors. Yet further refinements are necessary to decrease also the number of affected patients. © Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2014        PMID: 24687610     DOI: 10.1055/s-0033-1364030

Source DB:  PubMed          Journal:  Klin Padiatr        ISSN: 0300-8630            Impact factor:   1.349


  5 in total

1.  Administration of anticonvulsive rescue medication in children-discrepancies between parents' self-reports and limited practical performance.

Authors:  Almuth Kaune; Pia Madeleine Schumacher; Sabine Christine Hoppe; Steffen Syrbe; Matthias Karl Bernhard; Roberto Frontini; Andreas Merkenschlager; Wieland Kiess; Martina Patrizia Neininger; Astrid Bertsche; Thilo Bertsche
Journal:  Eur J Pediatr       Date:  2016-07-01       Impact factor: 3.183

2.  Knowledge of allergies and performance in epinephrine auto-injector use: a controlled intervention in preschool teachers.

Authors:  Henriette Karoline Dumeier; Luca Anne Richter; Martina Patrizia Neininger; Freerk Prenzel; Wieland Kiess; Astrid Bertsche; Thilo Bertsche
Journal:  Eur J Pediatr       Date:  2018-01-31       Impact factor: 3.183

3.  Managing of oral medicines in paediatric oncology: can a handbook and a pharmaceutical counselling intervention for patients and their parents prevent knowledge deficits? A pilot study.

Authors:  Janine Zimmer; Dorothee Niemann; Kirsten Seltmann; Lars Fischer; Holger Christiansen; Roberto Frontini; Wieland Kiess; Martina P Neininger; Astrid Bertsche; Thilo Bertsche
Journal:  Eur J Hosp Pharm       Date:  2015-09-24

Review 4.  Interventions to reduce medication errors in neonatal care: a systematic review.

Authors:  Minh-Nha Rhylie Nguyen; Cassandra Mosel; Luke E Grzeskowiak
Journal:  Ther Adv Drug Saf       Date:  2017-12-28

5.  Drug-handling problems and expectations of the ideal pediatric drug-reported by children and their parents.

Authors:  Birthe Herziger; Sarah Jeschke; Ruth Melinda Müller; Martina Patrizia Neininger; Thilo Bertsche; Astrid Bertsche
Journal:  Eur J Pediatr       Date:  2022-02-23       Impact factor: 3.860

  5 in total

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