Literature DB >> 24686798

Chest pain with raised troponin, ECG changes but normal coronary arteries.

Ayesha Amjad1, Amjad Ali, Ahmed Bashir, Muhammed Ali, Muhammad Najeeb Azam.   

Abstract

A 65-year-old woman presented to A&E department, with acute onset central chest pain and dyspnoea. ECG showed dynamic T wave changes while 12 h troponin was elevated. A diagnosis of acute coronary syndrome was made and she underwent an inpatient coronary angiogram. Although her coronary arteries were normal, symptoms persisted and D-dimers were found to be elevated. This led to a CT pulmonary angiogram, which ruled out pulmonary embolism, but uncovered a large ascending aortic aneurysm with a contained leak. She was immediately transferred to regional cardiothoracic unit for urgent surgical intervention. This case report illustrates the importance of a good clinical history, physical examination and timely investigations. It also emphasises that not all chest pain events with elevated troponin level are due to acute coronary syndrome and that alternative diagnoses should still be considered.

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Year:  2014        PMID: 24686798      PMCID: PMC3975511          DOI: 10.1136/bcr-2013-201975

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  11 in total

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Journal:  J Cardiovasc Pharmacol Ther       Date:  2004-09       Impact factor: 2.457

3.  Evaluation of the diagnostic and prognostic value of plasma D-dimer for abdominal aortic aneurysm.

Authors:  Jonathan Golledge; Reinhold Muller; Paula Clancy; Moira McCann; Paul E Norman
Journal:  Eur Heart J       Date:  2010-06-08       Impact factor: 29.983

Review 4.  Differential diagnosis of elevated troponins.

Authors:  Susanne Korff; Hugo A Katus; Evangelos Giannitsis
Journal:  Heart       Date:  2006-07       Impact factor: 5.994

5.  ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC).

Authors:  Christian W Hamm; Jean-Pierre Bassand; Stefan Agewall; Jeroen Bax; Eric Boersma; Hector Bueno; Pio Caso; Dariusz Dudek; Stephan Gielen; Kurt Huber; Magnus Ohman; Mark C Petrie; Frank Sonntag; Miguel Sousa Uva; Robert F Storey; William Wijns; Doron Zahger
Journal:  Eur Heart J       Date:  2011-08-26       Impact factor: 29.983

6.  How many patients with acute dissection of the thoracic aorta would erroneously receive thrombolytic therapy based on the electrocardiographic findings on admission?

Authors:  P Weiss; I Weiss; M Zuber; R Ritz
Journal:  Am J Cardiol       Date:  1993-12-01       Impact factor: 2.778

Review 7.  Aortic dissection in the thrombolytic era: early recognition and optimal management is a prerequisite for increased survival.

Authors:  T Melchior; D Hallam; B E Johansen
Journal:  Int J Cardiol       Date:  1993-11       Impact factor: 4.164

8.  Elevated plasma D-dimer and hypersensitive C-reactive protein levels may indicate aortic disorders.

Authors:  Shi-Min Yuan; Yong-Hui Shi; Jun-Jun Wang; Fang-Qi Lü; Song Gao
Journal:  Rev Bras Cir Cardiovasc       Date:  2011 Oct-Dec

9.  Evaluation of a "triple rule-out" coronary CT angiography protocol: use of 64-Section CT in low-to-moderate risk emergency department patients suspected of having acute coronary syndrome.

Authors:  Kevin M Takakuwa; Ethan J Halpern
Journal:  Radiology       Date:  2008-08       Impact factor: 11.105

Review 10.  The diagnosis and management of aortic dissection.

Authors:  Sri G Thrumurthy; Alan Karthikesalingam; Benjamin O Patterson; Peter J E Holt; Matt M Thompson
Journal:  BMJ       Date:  2011-01-11
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