Literature DB >> 24686200

Diabetes. Cognitive decline and T2DM--a disconnect in the evidence?

Mark W J Strachan1, Jacqueline F Price2.   

Abstract

Type 2 diabetes mellitus is associated with an increased risk of cognitive decline and dementia. Observational data suggest that hyperglycaemia, hypertension and dyslipidaemia might be involved in the causal pathway underlying this link, but data from the ACCORD MIND investigators challenge these findings. Why are the findings of observational and intervention studies so disconnected?

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Year:  2014        PMID： 24686200     DOI： 10.1038/nrendo.2014.38

Source DB:  PubMed          Journal:  Nat Rev Endocrinol        ISSN： 1759-5029            Impact factor:   43.330


  10 in total

1.  Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy.

Authors:  Lenore J Launer; Michael E Miller; Jeff D Williamson; Ron M Lazar; Hertzel C Gerstein; Anne M Murray; Mark Sullivan; Karen R Horowitz; Jingzhong Ding; Santica Marcovina; Laura C Lovato; James Lovato; Karen L Margolis; Patrick O'Connor; Edward W Lipkin; Joy Hirsch; Laura Coker; Joseph Maldjian; Jeffrey L Sunshine; Charles Truwit; Christos Davatzikos; R Nick Bryan
Journal:  Lancet Neurol       Date:  2011-09-28       Impact factor: 44.182

Review 2.  Statins for the prevention of dementia.

Authors:  Bernadette McGuinness; David Craig; Roger Bullock; Peter Passmore
Journal:  Cochrane Database Syst Rev       Date:  2009-04-15

3.  Effects of intensive blood-pressure control in type 2 diabetes mellitus.

Authors:  William C Cushman; Gregory W Evans; Robert P Byington; David C Goff; Richard H Grimm; Jeffrey A Cutler; Denise G Simons-Morton; Jan N Basile; Marshall A Corson; Jeffrey L Probstfield; Lois Katz; Kevin A Peterson; William T Friedewald; John B Buse; J Thomas Bigger; Hertzel C Gerstein; Faramarz Ismail-Beigi
Journal:  N Engl J Med       Date:  2010-03-14       Impact factor: 91.245

4.  Effects of combination lipid therapy in type 2 diabetes mellitus.

Authors:  Henry N Ginsberg; Marshall B Elam; Laura C Lovato; John R Crouse; Lawrence A Leiter; Peter Linz; William T Friedewald; John B Buse; Hertzel C Gerstein; Jeffrey Probstfield; Richard H Grimm; Faramarz Ismail-Beigi; J Thomas Bigger; David C Goff; William C Cushman; Denise G Simons-Morton; Robert P Byington
Journal:  N Engl J Med       Date:  2010-03-14       Impact factor: 91.245

5.  Designing prevention programmes to reduce incidence of dementia: prospective cohort study of modifiable risk factors.

Authors:  K Ritchie; I Carrière; C W Ritchie; C Berr; S Artero; M-L Ancelin
Journal:  BMJ       Date:  2010-08-05

6.  Effects of intensive glucose lowering in type 2 diabetes.

Authors:  Hertzel C Gerstein; Michael E Miller; Robert P Byington; David C Goff; J Thomas Bigger; John B Buse; William C Cushman; Saul Genuth; Faramarz Ismail-Beigi; Richard H Grimm; Jeffrey L Probstfield; Denise G Simons-Morton; William T Friedewald
Journal:  N Engl J Med       Date:  2008-06-06       Impact factor: 91.245

Review 7.  Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia.

Authors:  Bernadette McGuinness; Stephen Todd; Peter Passmore; Roger Bullock
Journal:  Cochrane Database Syst Rev       Date:  2009-10-07

8.  Cognitive function and brain structure in persons with type 2 diabetes mellitus after intensive lowering of blood pressure and lipid levels: a randomized clinical trial.

Authors:  Jeff D Williamson; Lenore J Launer; R Nick Bryan; Laura H Coker; Ronald M Lazar; Hertzel C Gerstein; Anne M Murray; Mark D Sullivan; Karen R Horowitz; Jingzhong Ding; Santica Marcovina; Laura Lovato; James Lovato; Karen L Margolis; Christos Davatzikos; Joshua Barzilay; Henry N Ginsberg; Peter E Linz; Michael E Miller
Journal:  JAMA Intern Med       Date:  2014-03       Impact factor: 21.873

Review 9.  Diabetes and other vascular risk factors for dementia: which factor matters most? A systematic review.

Authors:  Raoul P Kloppenborg; Esther van den Berg; L Jaap Kappelle; Geert Jan Biessels
Journal:  Eur J Pharmacol       Date:  2008-03-04       Impact factor: 4.432

Review 10.  Cognitive function, dementia and type 2 diabetes mellitus in the elderly.

Authors:  Mark W J Strachan; Rebecca M Reynolds; Riccardo E Marioni; Jacqueline F Price
Journal:  Nat Rev Endocrinol       Date:  2011-02       Impact factor: 43.330
  10 in total
  4 in total

1.  Longitudinal Cognitive Profiles in Diabetes: Results From the National Alzheimer's Coordinating Center's Uniform Data.

Authors:  Mary Sano; Carolyn W Zhu; Hillel Grossman; Corbett Schimming
Journal:  J Am Geriatr Soc       Date:  2017-08-03       Impact factor: 5.562

2.  Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain.

Authors:  Bora Inceoglu; Ahmed Bettaieb; Carlos A Trindade da Silva; Kin Sing Stephen Lee; Fawaz G Haj; Bruce D Hammock
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-06       Impact factor: 11.205

Review 3.  Brain alterations and clinical symptoms of dementia in diabetes: aβ/tau-dependent and independent mechanisms.

Authors:  Naoyuki Sato; Ryuichi Morishita
Journal:  Front Endocrinol (Lausanne)       Date:  2014-09-05       Impact factor: 5.555

4.  Tractography in Type 2 Diabetes Mellitus With Subjective Memory Complaints: A Diffusion Tensor Imaging Study.

Authors:  Jun Wang; Laiyang Ma; Guangyao Liu; Wenjuan Bai; Kai Ai; Pengfei Zhang; Wanjun Hu; Jing Zhang
Journal:  Front Neurosci       Date:  2022-04-06       Impact factor: 5.152
  4 in total

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