Literature DB >> 2468565

Antisense RNA: its functions and applications in gene regulation--a review.

M Inouye1.   

Abstract

All known antisense RNAs existing in nature are described. Of 11 natural antisense RNAs, nine function at the level of transcription and two at the level of DNA replication. On the basis of their inhibitory mechanisms they can be separated into three classes. From what can be found in the naturally occurring antisense RNAs, strategies in designing artificial antisense RNAs for gene expression are proposed, and applications and potential problems discussed.

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Year:  1988        PMID： 2468565     DOI： 10.1016/0378-1119(88)90124-2

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  50 in total

1.  Improvement and optimization of two engineered phage resistance mechanisms in Lactococcus lactis.

Authors:  S McGrath; G F Fitzgerald; D van Sinderen
Journal:  Appl Environ Microbiol       Date:  2001-02       Impact factor: 4.792

Review 2.  Modification and repression of genes expressed in the mammary gland using gene targeting and other technologies.

Authors:  J L Vilotte; P L'Huillier; J C Mercier
Journal:  J Mammary Gland Biol Neoplasia       Date:  1998-07       Impact factor: 2.673

3.  Drug target validation: lethal infection blocked by inducible peptide.

Authors:  J Tao; P Wendler; G Connelly; A Lim; J Zhang; M King; T Li; J A Silverman; P R Schimmel; F P Tally
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-18       Impact factor: 11.205

4.  RNA editing and regulation of Drosophila 4f-rnp expression by sas-10 antisense readthrough mRNA transcripts.

Authors:  Nick T Peters; Justin A Rohrbach; Brian A Zalewski; Colleen M Byrkett; Jack C Vaughn
Journal:  RNA       Date:  2003-06       Impact factor: 4.942

5.  A plant virus satellite RNA exhibits a significant sequence complementarity to a chloroplast tRNA.

Authors:  C Masuta; S Kuwata; T Matzuzaki; Y Takanami; A Koiwai
Journal:  Nucleic Acids Res       Date:  1992-06-11       Impact factor: 16.971

Review 6.  Genetic engineering of plants for virus resistance.

Authors:  F Gadani; L M Mansky; R Medici; W A Miller; J H Hill
Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

7.  Inhibition of gene expression by a short sense fragment.

Authors:  F H Cameron; P A Jennings
Journal:  Nucleic Acids Res       Date:  1991-02-11       Impact factor: 16.971

8.  Inhibition of flower pigmentation by antisense CHS genes: promoter and minimal sequence requirements for the antisense effect.

Authors:  A R van der Krol; L A Mur; P de Lange; J N Mol; A R Stuitje
Journal:  Plant Mol Biol       Date:  1990-04       Impact factor: 4.076

9.  Cloning, expression, and sequence determination of a bacteriophage fragment encoding bacteriophage resistance in Lactococcus lactis.

Authors:  C Hill; L A Miller; T R Klaenhammer
Journal:  J Bacteriol       Date:  1990-11       Impact factor: 3.490

10.  Specific gene suppression by engineered ribozymes in monkey cells.

Authors:  F H Cameron; P A Jennings
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205
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